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2 results on '"Lin Lin Tong"'

1. Is the prediction of prognosis not improved by the seventh edition of the TNM classification for colorectal cancer? Analysis of the surveilla006Ece, epidemiology, and end results (SEER) database

Author

Miao Yu, Ying-Ying Xu, Yongxi Song, Jingxu Sun, Zhenning Wang, Lin-lin Tong, Huimian Xu, and Peng Gao

Subjects
Oncology, End results, Male, Cancer Research, medicine.medical_specialty, Colorectal cancer, Seer database, Kaplan-Meier Estimate, TNM staging system, Predictive Value of Tests, Internal medicine, Epidemiology, Genetics, Medicine, Stage iib, Humans, Stage (cooking), Aged, Neoplasm Staging, Aged, 80 and over, business.industry, Cancer, TNM system, Middle Aged, medicine.disease, Prognosis, Prognostic prediction, Lymphatic Metastasis, Female, business, Colorectal Neoplasms, Research Article, SEER Program
Abstract

Background Whether the 7th edition of American Joint Committee on Cancer (AJCC) TNM staging system (AJCC-7) is a successful revision remains debatable. We aimed to compare the predictive capacity of the AJCC-7 for colorectal cancer with the 6th edition of the AJCC TNM staging system (AJCC-6). Methods The National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) dataset consisting of 158,483 records was used in this study. We evaluated the predictive capacity of the two editions of the staging system using Harrell’s C index and Bayesian Information Criterion (BIC). Results There was a significant prognostic difference between patients at stage IIB and IIC (P Conclusions This study demonstrates that AJCC-7 is superior to the AJCC-6 staging system in predictive capacity.

Published
2013

2. Is the prediction of prognosis not improved by the seventh edition of the TNM classification for colorectal cancer? Analysis of the surveilla006Ece, epidemiology, and end results (SEER) database.

Author

Peng Gao, Yong-xi Song, Zhen-ning Wang, Ying-ying Xu, Lin-lin Tong, Jing-xu Sun, Miao Yu, and Hui-mian Xu

Subjects
PROGNOSIS, COLON cancer, EPIDEMIOLOGY, STANDARD deviations
Abstract

Background: Whether the 7th edition of American Joint Committee on Cancer (AJCC) TNM staging system (AJCC-7) is a successful revision remains debatable. We aimed to compare the predictive capacity of the AJCC-7 for colorectal cancer with the 6th edition of the AJCC TNM staging system (AJCC-6). Methods: The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) dataset consisting of 158,483 records was used in this study. We evaluated the predictive capacity of the two editions of the staging system using Harrell's C index and Bayesian Information Criterion (BIC). Results: There was a significant prognostic difference between patients at stage IIB and IIC (P < 0.001). Stage III patients with similar prognoses were adequately sub-grouped in the same stage according to AJCC-7. The Harrell's C index revealed a value of 0.7692 for AJCC-7, which was significantly better than 0.7663 for AJCC-6 (P < 0.001). BIC analysis provided consistent results (P < 0.001). Conclusions: This study demonstrates that AJCC-7 is superior to the AJCC-6 staging system in predictive ca [ABSTRACT FROM AUTHOR]

Published
2013
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