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1. 19th International Conference on Dialysis, Advances in Chronic Kidney Disease 2017, February 1-3, 2017, Las Vegas, NV: Abstracts

Author

Graziella D'Arrigo, Zhonghua Liu, José F. Pessanha, Xiaoling Ye, Inne Hendrickx, Stephan Thijssen, Zhen Cheng, George A. Kaysen, Schantel Williams, Antoine G. Schneider, Seung Duk Hwang, Druckerei Stückle, Jorge Cerdá, Sandra Wray, Aashish Sharma, Edmundo I. Cabrera-Fischer, Soo Jeong Choi, Silvia De Rosa, Pierre Schläpfer, Michael J. Connor, Sri Lekha Tummalapalli, Tsering Dhondup, Chris Anstey, Jin Kuk Kim, Abdulmecit Yildiz, Vanja Persic, Mariele Gobo-Oliveira, Jay L. Koyner, Sabrina Milan Manani, Yuxin Nie, Marta Proglio, Mark D. Okusa, Claudio Ronco, Michelle M.Y. Wong, Xinghua Chen, Azra Bihorac, Rodolfo Valtuille, Shi-xiang Wang, Hanjie Zhang, Zhen Zhang, Laura M. Rosales, Yanna Dou, Marcee Bonner, Ling Yu, Bo Shen, Huiming Wang, Xiaohong Chen, Peter Kotanko, Fiorella Gastaldon, Abhilash Koratala, Jianzhou Zou, André Luis Balbi, Xuesen Cao, Rinaldo Bellomo, Bo Yeon Kim, Cintia Galli, Daniel Marsh, Anna Meyring-Wösten, Amir Kazory, Rocco Ferrandino, Lili Chan, Ahmed Kayssi, Anja Kruse, Francesco Galli, Viola Van Gorp, Davide Bolignano, Alberto Ortiz, Richard F. Neville, Daniel Bia, Lilia Rizo-Topete, Patrick M. Honore, Rajit K. Basu, Kent Doi, Zoltan H. Endre, Giovanni Tripepi, Anitha Vijayan, Mitchell H. Rosner, Sarah Faubel, Ladan Golestaneh, Nathan W. Levin, Jie Ma, Maggie Han, Kinsuk Chauhan, Yanina Zócalo, D.J. Askenazi, Magdalena Madero, Priti Poojary, Herbert D. Spapen, Yuedong Wang, Rossella Baggetta, Paul Martin, Gianluca Villa, Elisabeth De Waele, Aparna Saha, Ricardo L. Armentano, Adrian Covic, Xiaoqiang Ding, Jinbo Yu, Girish N. Nadkarni, Yalcin Solak, Jouke De Regt, Michel Jadoul, Alessandra Brocca, Hisako Saito, Han Li, Mehmet Kanbay, Débora M. Soares, Yujuan Wang, Juan C Ramirez-Sandoval, Michael Heung, Laura Rosales, L. Gabriela Sánchez-Lozada, Mahmut Ilker Yilmaz, Masayuki Tanemoto, Cristiano Chiappa, Grazia Maria Virzì, Len A. Usvyat, Georges Ouellet, Sun Young Jang, Sara Samoni, Viktoriya Kuntsevich, Jean-Daniel Durovray, Dimitrie Siriopol, Candace Young, Qi Qian, Il Sang Shin, Jili Zhu, Rita Jacobs, Valery Plouhinec, Daniela Ponce, Yu Ishimoto, and Cesar Flores Gama

Subjects
Gerontology, medicine.medical_specialty, Las vegas, business.industry, medicine.medical_treatment, Hematology, General Medicine, medicine.disease, Nephrology, Emergency medicine, medicine, business, Dialysis, Kidney disease
Published
2017
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2. Selected Abstracts from the 32nd International Vicenza Course on Hemodialysis and Peritoneal Dialysis. Vicenza, June 10-13, 2014: Abstracts

Author

Piet M. ter Wee, Peter F Mount, Muriel P.C. Grooteman, Ugo Vertolli, Peter Kotanko, Frank M. van der Sande, Jose A. Diaz-Buxo, Rosa Carmello, Li Liu, Mayuri Thakuria, Len A. Usvyat, Yuqing Chen, Yalcin Solak, Renée Lévesque, Daniel E. Weiner, Xuyang Cheng, Matthew A. Roberts, Mumtaz Takir, Samir S. Patel, Marinus A. van den Dorpel, Claudio Ronco, Ira M. Mostovaya, Jing Deng, Abduzhappar Gaipov, Li Zuo, Maria Pia Rodighiero, Druckerei Stückle, Francesca Martino, Lakhmir S. Chawla, Michael G. Seneff, Goran Imamović, Linda H. Ficociello, Zhenhui Tao, Lu Yuan, Claudy Mullon, Scott P. Sibbel, Jason Chuen, Yusu Jian, Catarina Teixeira, Mitchel Rosner, Michelle M.Y. Wong, Michael Black, Semir Imamović, Michiel L. Bots, Thomas J. Alfieri, Ashte Collins, Menso J. Nubé, Camilla Rubini, Karel M.L. Leunissen, Hongmei Liu, Peter J. Blankestijn, Mehmet Kanbay, Isabelle Chapdelaine, Satz Mengensatzproduktion, Mardiana Lee, Yuedong Wang, Jeroen P. Kooman, Yong Wu, Lorenzo A. Calò, Maree-Ross Smith, Tom Cornelis, Carlo Crepaldi, Lourdes Blanca Martos, Lihua Chen, Jan H.M. Tordoir, Lindita Shehu, Ermira Brasha-Mitchell, Hongbo Liu, Xiang Li, and Agostino Naso

Subjects
medicine.medical_specialty, Nephrology, business.industry, medicine.medical_treatment, Emergency medicine, Medicine, Hematology, General Medicine, Hemodialysis, business, Intensive care medicine, Peritoneal dialysis
Published
2014
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3. Vascular Access Vulnerability in Intensive Hemodialysis: A Significant Achilles' Heel?

Author

Yuedong Wang, Frank M. van der Sande, Jan H.M. Tordoir, Karel M.L. Leunissen, Peter Kotanko, Len A. Usvyat, Michelle M.Y. Wong, Jeroen P. Kooman, Tom Cornelis, Interne Geneeskunde, Surgery, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, RS: CARIM - R3 - Vascular biology, and MUMC+: MA Nefrologie (9)

Subjects
Male, medicine.medical_specialty, Complications, Heel, LONG-TERM, Fistula, medicine.medical_treatment, Arteriovenous fistula, INCREASED EXPRESSION, Quality of life, QUALITY-OF-LIFE, Renal Dialysis, Risk Factors, Internal medicine, DIALYSIS, medicine, Humans, FREQUENT HEMODIALYSIS, 3 TIMES, Dialysis, HOME HEMODIALYSIS, CONVENTIONAL HEMODIALYSIS, business.industry, Home hemodialysis, Hematology, General Medicine, medicine.disease, Surgery, Catheter, medicine.anatomical_structure, Nephrology, Hemodialysis, SURVIVAL, Female, Vascular access, business, NOCTURNAL HEMODIALYSIS, Vascular Access Devices
Abstract

Background: Frequent hemodialysis (HD) may be associated with an increased risk of vascular access complications. Studies addressing vascular access outcomes in frequent HD show conflicting results. Methods: We searched Medline for trials looking at vascular access outcomes in frequent HD. Results: Nineteen studies met the inclusion criteria; only studies with a control group were included for analysis (n = 15). The vascular access event rate was higher in intensive HD as compared to conventional HD (difference of 6.7 events per 100 patient-years, p = 0.009). Overall event rates were not significantly different between conventional and intensive HD when stratified for access type, but were notably higher in the arteriovenous grafts and catheter group as compared to the arteriovenous fistula (AVF) group. Conclusion: Intensive HD is associated with an increased risk of vascular access complications. Overall reported event rates were lower in the AVF group. Further controlled studies should investigate whether a ‘fistula first' strategy may be recommended also for intensive HD.

Published
2014
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4. Correlation between Inflammatory Biomarkers and Red Blood Cell Life Span in Chronic Hemodialysis Patients

Author

Vanja Persic, Nathan W. Levin, Laura Rosales, Jie Ma, Schantel Williams, Hanjie Zhang, Peter Kotanko, Georges Ouellet, Michelle M.Y. Wong, Yuedong Wang, Yanna Dou, Stephan Thijssen, Anja Kruse, and Viktoriya Kuntsevich

Subjects
Adult, Male, medicine.medical_specialty, Anemia, medicine.medical_treatment, 030232 urology & nephrology, Inflammation, 030204 cardiovascular system & hematology, Gastroenterology, Blood Urea Nitrogen, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Renal Dialysis, Internal medicine, medicine, Humans, Blood urea nitrogen, Aged, business.industry, Interleukin, Hematology, General Medicine, Erythrocyte Aging, Middle Aged, medicine.disease, Uric Acid, Red blood cell, medicine.anatomical_structure, Endocrinology, chemistry, Nephrology, Uric acid, Kidney Failure, Chronic, Female, Hemodialysis, medicine.symptom, business, Biomarkers
Abstract

Background and Objectives: The pathogenesis of anemia in hemodialysis (HD) patients is dependent on multiple factors, with decreased red blood cell life span (RBCLS) being a significant contributor. Although the impact of reduced RBCLS on anemia is recognized, it is still a subject that is not well researched. The objective of this study was to investigate the relationship between RBCLS and inflammatory biomarkers in chronic HD patients. Design, Setting, Participants, and Measurements: RBCLS was calculated from alveolar carbon monoxide concentrations measured by gas chromatography. Interleukins (IL) IL-6, IL-18, IL-10, and high sensitivity C-reactive protein were measured using bead-based multiplex assay. Measurements were carried out at baseline and during follow-up. The associations between RBCLS and inflammatory biomarkers were evaluated using linear mixed effects models. Results: RBCLS measurements were available for 54 HD patients. Their average age was 58.5 ± 14.4 years, 68.5% were males, 48.1% were diabetics, and the HD vintage was 51 ± 48 months. In 4 patients, RBCLS was measured once, while in 50 patients, up to 5 repeated RBCLS measurements were available. RBCLS was 73.2 ± 17.8 days (range 37.7-115.8 days). No association was found between RBCLS and any of the inflammatory biomarkers. Of note, RBCLS was positively correlated with levels of uric acid (p = 0.02) and blood urea nitrogen (BUN; p = 0.01), respectively. Conclusion: Our study suggests that inflammation pathways reported by these biomarkers only have a limited role in causing premature RBC death. The positive correlation with uric acid and BUN warrants further studies.

Published
2017

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