1. The association between changes in blood pressure components and incident cardiovascular diseases
- Author
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Donna Parizadeh, Hosein Ghahvehchian, Samaneh Asgari, Amir Abbas Momenan, Fereidoun Azizi, and Farzad Hadaegh
- Subjects
blood pressure change ,blood pressure components ,cardiovascular disease ,cohort ,population study ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Purpose: To determine the association of changes in blood pressure (BP) components between baseline examination (1999–2001) and a second visit (2002–2005) with incident cardiovascular diseases (CVD). Methods: In 3569 (2048 female) Iranian subjects ≥30 y, systolic BP, diastolic BP, mean arterial pressure (MAP) and pulse pressure (PP) were evaluated in two consecutive visits. Subjects were then followed for cardiovascular events. Multivariate sex-adjusted Cox Proportional-Hazards models were built for each BP component’s change, and further adjusted for baseline BP values, traditional cardiovascular risk factors, and their changes. Results: During a median follow-up of 6.09 years after the second examination, 303 CVD cases occurred. A 1 SD increase in systolic BP, diastolic BP and MAP were significantly associated with 21%, 22%, and 95% increased CVD risk after adjustments for baseline values of BP components and other common risk factors (all p-values
- Published
- 2017
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