41 results on '"ten Hacken, Elisa"'
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2. B Cell-Restricted Depletion of Dnmt3a Activates Notch Signaling and Causes Chronic Lymphocytic Leukemia
3. Richter syndrome: novel insights into the biology of transformation
4. HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment
5. Immuno-Genetic Changes Underlie Response to Immune Checkpoint Blockade Therapy in Richter's Syndrome Mouse Models
6. Targeting B-cell anergy in chronic lymphocytic leukemia
7. Targeting the LYN/HS1 signaling axis in chronic lymphocytic leukemia
8. HS1 has a central role in the trafficking and homing of leukemic B cells
9. Understanding CLL biology through mouse models of human genetics
10. Dissecting Richter's Syndrome in a Multiplexed CRISPR-Based Mouse Model Reveals Key Changes in MYC, Interferon and BCR Signaling Underlying Transformation
11. IKZF3 Overexpression Phenocopies Gain-of-Function Mutation in Chronic Lymphocytic Leukemia
12. Expression of Sf3b1-K700E accelerates the Development of Chronic Lymphocytic Leukemia in a Del(13q) Murine Model
13. Multiplexed CRISPR In Vivo Editing of CLL Loss-of-Function Lesions Models Transformation of Chronic Lymphocytic Leukemia into Richter's Syndrome
14. RPS15 and TP53 Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model
15. Interrogation of Individual CLL Loss-of-Function Lesions By CRISPR In Vivo Editing Reveals Common and Unique Pathway Alterations
16. Identification of Genotype-Specific Therapeutic Vulnerabilities By Comparative Dynamic BH3 Profiling Analysis of Human and Murine CLL
17. MCL-1 and PKA/AMPK Axis Fuel Venetoclax Resistance in Lymphoid Cancers
18. B Cell Restricted Expression of Mutated IKZF3 modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL
19. KZF-L162R Mutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes
20. Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1 Mutation to Impact DNA Damage Response and BCR Signaling
21. HSP90, a chaperone that can make you SYK
22. IgM and IgD Receptors Differentially Contribute to CLL Survival and Chemokine Secretion: Implications for CLL Biology and Treatment
23. Identification of B Cell Receptor Antigens in the Chronic Lymphocytic Leukemia Microenvironment
24. Ibrutinib Targets Nurse-like Cells Supporting an Immunosuppressive Phenotype in Chronic Lymphocytic Leukemia
25. Correlation Between Clinical Responses and Immune Characteristics in Patients with Relapsed CLL Treated with Ofatumumab and Lenalidomide
26. Splicing Modulation Perturbs Key Survival Pathways and Sensitizes Chronic Lymphocytic Leukemia to Venetoclax Treatment
27. Nurse-like Cells Engage Sigm and Sigd on Chronic Lymphocytic Leukemia (CLL) Cells: Implications for BCR Signaling Activation and Functional Outcome
28. Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR+ B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism
29. Targeting the LYN/HS1 Signaling Axis in Chronic Lymphocytic Leukemia
30. Targeting B Cell Anergy in Chronic Lymphocytic Leukemia
31. RPS15and TP53Co-Mutation Drives B Cell Malignancy through Altered Translation and MYC Activation in a Murine Model
32. Expression of Sf3b1-K700Eaccelerates the Development of Chronic Lymphocytic Leukemia in a Del(13q) Murine Model
33. Multiplexed CRISPR In VivoEditing of CLL Loss-of-Function Lesions Models Transformation of Chronic Lymphocytic Leukemia into Richter's Syndrome
34. B Cell-Restricted Depletion of Dnmt3aActivates NotchSignaling and Causes Chronic Lymphocytic Leukemia
35. IKZF3Overexpression Phenocopies Gain-of-Function Mutation in Chronic Lymphocytic Leukemia
36. B Cell Restricted Expression of Mutated IKZF3modulates BCR Signaling and Homing Pathways in a Mouse Model of CLL
37. KZF-L162RMutation Affects Splenic Mature B Cell Development and Alters Expression of Aiolos Target Genes
38. Integrated Genomic and Proteomic Analysis of Murine CLL-like Cells Reveals SF3B1Mutation to Impact DNA Damage Response and BCR Signaling
39. Dynamic BH3 Profiling to Assess the Effects of Novel Agents on Anti-Apoptotic Protein Dependence of CLL Cells
40. The Clinical BET Inhibitor, GS-5829, Is Active Against Chronic Lymphocytic Leukemia As Single Agent and in Combination with B-Cell Receptor Signaling Inhibitors
41. Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR+B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism
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