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10 results on '"Young, Mary"'

1. Immune Cell Profiles in Patients Treated with Lenalidomide and Alternate Day Prednisolone Maintenance Post Upfront ASCT for Multiple Myeloma (LEOPARD Trial)

Author

Kalff, Anna, primary, Norton, Sam, additional, Khong, Tiffany, additional, Ramachandran, Malarmathy, additional, Young, Mary H., additional, Pierceall, William, additional, Thakurta, Anjan, additional, Oppermann, Udo, additional, Guo, Manman, additional, Reynolds, John, additional, and Spencer, Andrew, additional

Published
2020
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2. Multiplexed Immunofluorescence (IF) Analysis and Gene Expression Profiling of Biopsies from Patients with Relapsed/Refractory (R/R) Diffuse Large B Cell Lymphoma (DLBCL) Treated with Lisocabtagene Maraleucel (liso-cel) in Transcend NHL 001 Reveal Patterns of Immune Infiltration Associated with Durable Response

Author

Reiss, David J., primary, Do, Trevor, primary, Kuo, David, primary, Gray, Vanessa E., primary, Olson, N. Eric, primary, Lee, Chung-Wein, primary, Young, Mary H., primary, Srinivasan, Shradha, primary, Gray, Falon D., primary, Fox, Brian, primary, Couto, Suzana, primary, Dubovsky, Jason A., primary, Schmitz, Frank, primary, and Newhall, Kathryn, primary

Published
2019
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3. Baseline and on-Treatment Bone Marrow Microenvironments Predict Myeloma Patient Outcomes and Inform Potential Intervention Strategies

Author

Danziger, Samuel A, primary, McConnell, Mark, additional, Gockley, Jake, additional, Young, Mary, additional, Rosenthal, Adam, additional, Schmitz, Frank, additional, Reiss, David, additional, Farmer, Phil, additional, Ashby, Cody, additional, Bauer, Michael A, additional, van Rhee, Frits, additional, Davies, Faith E., additional, Zangari, Maurizio, additional, Petty, Nathan, additional, Copeland, Wilbert B., additional, Fox, Brian A., additional, Hoering, Antje, additional, Fitch, Alison, additional, Newhall, Katie, additional, Barlogie, Bart, additional, Walker, Brian A, additional, Trotter, Matthew, additional, Hershberg, Rob, additional, Dervan, Andrew, additional, Ratushny, Alexander, additional, and Morgan, Gareth, additional

Published
2018
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4. Deep Immunoprofiling of the Bone Marrow Microenvironmental Changes Underlying the Multistep Progression of Multiple Myeloma

Author

Young, Mary H, primary, Danziger, Sam A, additional, Fitch, Alison, additional, Schmitz, Frank, additional, Gockley, Jake, additional, McConnell, Mark, additional, Reiss, David, additional, Copeland, Wilbert B., additional, Johnson, Sarah K, additional, Newhall, Katie, additional, Hershberg, Robert, additional, Foy, Teri, additional, Ratushny, Alexander, additional, Walker, Brian A, additional, Dervan, Andrew, additional, and Morgan, Gareth, additional

Published
2018
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5. Immune Microenvironment Analysis of Bone Marrow By Mass Cytometry and RNA Sequencing in Multiple Myeloma Patients Treated with Daratumumab and Durvalumab

Author

Seymour, Frances, primary, Young, Mary H, additional, Tometsko, Mark, additional, Cavenagh, Jamie, additional, Thompson, Ethan G., additional, Whalen, Elizabeth, additional, Danziger, Sam A, additional, Fitch, Alison, additional, Fox, Brian A., additional, Dervan, Andrew, additional, Foy, Teri, additional, Newhall, Katie, additional, and Gribben, John G., additional

Published
2018
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7. Thrombocytopenia Is a Strong Predictor of All-Cause and AIDS-Specific Mortality in Women with HIV: The Women’s Interagency HIV Study.

Author

Pearce, C. Leigh, primary, Mack, Wendy J., additional, Levine, Alexandra M., additional, Gravink, Jay, additional, Cohen, Mardge H., additional, Machtinger, Edward L., additional, Anastos, Kathryn, additional, Silverberg, Michael J., additional, Young, Mary A., additional, Minkoff, Howard, additional, and Watts, D. Heather, additional

Published
2004
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10. Incidence of TEL/AML1Fusion in Children With Relapsed Acute Lymphoblastic Leukemia

Author

Loh, Mignon L., Silverman, Lewis B., Young, Mary L., Neuberg, Donna, Golub, Todd R., Sallan, Stephen E., and Gilliland, D. Gary

Abstract

The TEL/AML1fusion associated with t(12;21)(p13;q22) is the most common gene rearrangement in childhood leukemia, occurring in approximately 25% of pediatric acute lymphoblastic leukemia (ALL), and is associated with a favorable prognosis. For example, a cohort of pediatric patients with ALL retrospectively analyzed for theTEL/AML1fusion treated on Dana-Farber Cancer Institute (DFCI) ALL Consortium protocols between 1980 to 1991 demonstrated a 100% relapse-free survival in TEL/AML1-positive patients with a median of 8.3 years of follow-up. However, two recent studies analyzing pediatric patients with relapsed ALL have reported the same incidence of the TEL/AML1rearrangement as in patients with newly diagnosed ALL, suggesting that TEL/AML1positivity is not a favorable prognostic indicator. To clarify this apparent discrepancy, 48 pediatric patients treated on Dana-Farber Cancer Institute (DFCI) protocols with ALL at first or second relapse were tested forTEL/AML1using reverse transcriptase-polymerase chain reaction (RT-PCR). The TEL/AML1fusion was identified in only 1 of 32 analyzable relapsed ALL patients, in concordance with our previous reports of improved disease-free survival in TEL/AML1-positive patients. The low frequency of TEL/AML1-positive patients at relapse is significantly different than that reported in other studies. Although there are several potential explanations for the observed differences in TEL/AML1-positive patients at relapse, it is plausible that relapse-free survival in TEL/AML1-positive patients may be changed with different therapeutic approaches. Taken together, these results support the need for prospective analysis of prognosis in TEL/AML1-positive patients.

Published
1998
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