48 results on '"Yao Yu"'
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2. FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis
3. Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease
4. Base Editing for Therapeutic Induction of Fetal Hemoglobin in β-Thalassemia
5. Germline Loss-of-Function Mutations in MDM4 Cause p53-Dependent Hematopoietic Cell Death in Patients with Variable Bone Marrow Failure Phenotypes
6. Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development
7. SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models
8. High shear–dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction
9. Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System
10. A Novel RPS19-Edited Hematopoietic Stem Cell Model of Diamond-Blackfan Anemia for Development of Lentiviral Vector Gene Therapy
11. MicroRNA expression in maturing murine megakaryocytes
12. Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells
13. Adenosine Base Editing of γ-Globin Promoters Induces Fetal Hemoglobin and Inhibit Erythroid Sickling
14. CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies
15. Global regulation of erythroid gene expression by transcription factor GATA-1
16. Nonspecific inhibition of erythropoiesis by short hairpin RNAs
17. Regulation of gene expression by miR-144/451 during mouse erythropoiesis
18. The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation
19. FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1
20. Activated protein C cofactor function of protein S: a novel role for a γ-carboxyglutamic acid residue
21. Erythroid miRNA-144/451 Binds Many mRNAs but Regulates Only a Small Subset
22. Reduced Polycomb Repressor Complex 2 (PRC2) Activity and Increased TP53 Activity Mediate Hematopoietic Stem Cell Dysfunction in RPS19-Mutated Diamond-Blackfan Anemia
23. Iron Restriction Alleviates β-Thalassemia By Stimulating ULK1-Mediated Autophagy of Free α-Globin
24. Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines
25. Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts
26. The Distinct Clinical Features and Prognosis of the CD10+MUM1+ and CD10-Bcl6-MUM1- Diffuse Large B-Cell Lymphoma
27. A Novel Regulatory Region of the p27 Locus Is Required for Normal Erythroid p27 Expression, and Produces a Long Noncoding RNA with No Detectable Function
28. Chinese External Validation of the Cochrane Haematological Malignancies Group Prognostic Index for Chronic Lymphocytic Leukemia Patients
29. Temporally Distinct Developmental Waves of Erythropoiesis from Human Pluripotent Stem Cells
30. Chinese External Validation of the Cochrane Haematological Malignancies Group Prognostic Index for Chronic Lymphocytic Leukemia Patients
31. Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells
32. Germline Loss-of-Function Mutations in MDM4Cause p53-Dependent Hematopoietic Cell Death in Patients with Variable Bone Marrow Failure Phenotypes
33. Species-Specific Functions For Long Noncoding RNAs During Erythropoeisis
34. Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function
35. Trisomy 21 enhances human fetal erythro-megakaryocytic development
36. Trim58 Is a Putative E3 Ubiquitin Ligase That Functions in Late Stage Erythropoiesis
37. Modeling Congenital Dyserythropoietic Anemia Type I Through Patient-Derived Induced Pluripotent Stem Cells
38. Long Noncoding RNAs in Erythropoiesis and Megakaryopoiesis.
39. Loss of miR-451alleviates β-thalassemia by stimulating ULK1-mediated autophagy of free α-globin
40. Patient-Derived Induced Pluripotent Stem Cells Reveal Distinct Hematopoietic Defects Conferred by Trisomy 21 and Truncated GATA-1
41. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate
42. Graded Repression of PU.1 Expression by GATA Factors Influence Hematopoietic Progenitor Cell Fate
43. The microRNA144/451 Locus Enhances Nuclear FOXO3a Activity to Protect Erythroid Cells against Oxidant Stress
44. Graded repression of PU.1/Sfpi1gene transcription by GATA factors regulates hematopoietic cell fate
45. CRISPR-Cas9 Genome Editing of ?-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of ß-Hemoglobinopathies
46. The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBGPromoter DNA Methylation
47. Inducible Gata1Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells
48. Activated protein C cofactor function of protein S: a novel role for a γ-carboxyglutamic acid residue.
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