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18 results on '"Pasricha, Sant‐Rayn"'

1. Iron homeostasis governs erythroid phenotype in polycythemia vera

Author

Bennett, Cavan, Jackson, Victoria E., Pettikiriarachchi, Anne, Hayman, Thomas, Schaeper, Ute, Moir-Meyer, Gemma, Fielding, Katherine, Ataide, Ricardo, Clucas, Danielle, Baldi, Andrew, Garnham, Alexandra L., Li-Wai-Suen, Connie S. N., Loughran, Stephen J., Baxter, E. Joanna, Green, Anthony R., Alexander, Warren S., Bahlo, Melanie, Burbury, Kate, Ng, Ashley P., and Pasricha, Sant-Rayn

Published
2023
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2. Erythroferrone inhibits the induction of hepcidin by BMP6

Author

Arezes, João, Foy, Niall, McHugh, Kirsty, Sawant, Anagha, Quinkert, Doris, Terraube, Virginie, Brinth, Alette, Tam, May, LaVallie, Edward R., Taylor, Stephen, Armitage, Andrew E., Pasricha, Sant-Rayn, Cunningham, Orla, Lambert, Matthew, Draper, Simon J., Jasuja, Reema, and Drakesmith, Hal

Published
2018
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5. Defining Anaemia across the Lifecycle in Healthy Reference Populations: An Analysis for Guideline Development

Author

Fielding, Katherine L, primary, Braat, Sabine, additional, Davidson, Eliza, additional, Moir-Meyer, Gemma, additional, Zaloumis, Sophie, additional, Xu Hui Xu, Jessica, additional, Blaauwendraad, Sophia M, additional, Jaddoe, Vincent W.V., additional, Gaillard, Romy, additional, Parkin, Patricia C, additional, Borkhoff, Cornelia M, additional, Keown-Stoneman, Charles D., additional, Birken, Catherine S, additional, Maguire, Jonathon L, additional, and Pasricha, Sant-Rayn, additional

Published
2022
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10. Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

Author

Arezes, João, primary, Foy, Niall, primary, McHugh, Kirsty, primary, Quinkert, Doris, primary, Benard, Susan, primary, Sawant, Anagha, primary, Frost, Joe N., primary, Armitage, Andrew E., primary, Pasricha, Sant-Rayn, primary, Lim, Pei Jin, primary, Tam, May S., primary, Lavallie, Edward, primary, Pittman, Debra D., primary, Cunningham, Orla, primary, Lambert, Matthew, primary, Murphy, John E., primary, Draper, Simon J., primary, Jasuja, Reema, primary, and Drakesmith, Hal, primary

Published
2020
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11. Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia

Author

Arezes, Joao, primary, Foy, Niall, primary, Benard, Susan, primary, Sawant, Anagha, primary, Tam, May S, primary, Maben, Zachary, primary, McHugh, Kirsty, primary, Quinkert, Doris, primary, Armitage, Andrew E, primary, Pasricha, Sant-Rayn, primary, Lim, Pei-Jin, primary, Frost, Joe, primary, LaVallie, Edward, primary, Cunningham, Orla, primary, Lambert, Matthew, primary, Pittman, Debra D, primary, Murphy, John E., primary, Draper, Simon J, primary, Jasuja, Reema, primary, and Drakesmith, Alexander, primary

Published
2019
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13. Hepcidin and Erythroferrone Levels across Human Pregnancy, and the Effect of IV Iron Infusion - a Revamp Substudy

Author

Fielding, Katherine, Mwangi, Martin, Moya, Ernest, Ataide, Ricardo, Mzembe, Glory, Randall, Louise, Braat, Sabine, Harding, Rebecca, Phiri, Kamija S., and Pasricha, Sant-Rayn

Abstract

Hepcidin is known to be suppressed in human pregnancy; and while it's known that intravenous iron infusion increases hepcidin levels, it is unknown to what degree this occurs during pregnancy.

Published
2023
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14. Tmprss6siRNA Treatment in Mice Stops Hepcidin Reduction across Pregnancy

Author

Fielding, Katherine, Ataide, Ricardo, Bennett, Cavan, Pettikiriarachchi, Anne, Clucas, Danielle, Schaeper, Ute, and Pasricha, Sant-Rayn

Abstract

Aim:Hepcidin levels are suppressed during human and murine pregnancy. It is unknown whether hepcidin levels are primarily the result of iron deficiency/utilisation or whether there is a pregnancy-specific mechanism for hepcidin suppression. We reasoned that Tmprss6inhibition would cause constitutive BMP-SMAD signalling and help determine the mechanism of antenatal hepcidin suppression.

Published
2023
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