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13 results on '"Oki, Kentaro"'

1. A Nationwide Clinical Trial ALL-B12: An Optimized Therapy for Pediatric B-Precursor Acute Lymphoblastic Leukemia with Excellent Overall Survival and Minimal Non-Relapse Mortality: A Report from the Japan Children's Cancer Group

Author

Kato, Motohiro, Okamoto, Yasuhiro, Imamura, Toshihiko, Kada, Akiko, Saito, Akiko M, Iijima-Yamashita, Yuka, Deguchi, Takao, Oki, Kentaro, Fukushima, Takashi, Anami, Ken-ichi, Sanada, Masashi, Taki, Tomohiko, Hashii, Yoshiko, Kiyokawa, Nobutaka, Kosaka, Yoshiyuki, Yoshida, NAO, Yuza, Yuki, Yanagimachi, Masakatsu, Watanabe, Kenichiro, Sato, Atsushi, Imai, Chihaya, Taga, Takashi, Adachi, Souichi, Horibe, Keizo, Manabe, Atsushi, and Koh, Katsuyoshi

Published
2023
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2. The Detection of Minor Clones with Somatic KIT D816V Mutations Using Droplet Digital PCR in Pediatric De Novo AML: AML-05 Trial from the Japanese Pediatric Leukemia/Lymphoma Study Group

Author

Sasaki, Koji, primary, Uchiyama, Yuri, additional, Ikeda, Junji, additional, Yoshitomi, Masahiro, additional, Shimosato-Wada, Yuko, additional, Tokumasu, Mayu, additional, Matsuo, Hidemasa, additional, Yoshida, Kenichi, additional, Oki, Kentaro, additional, Yamato, Genki, additional, Hara, Yusuke, additional, Kinoshita, Akitoshi, additional, Tomizawa, Daisuke, additional, Taga, Takashi, additional, Adachi, Souichi, additional, Tawa, Akio, additional, Horibe, Keizo, additional, Matsumoto, Naomichi, additional, Ito, Shuichi, additional, Hayashi, Yasuhide, additional, and Shiba, Norio, additional

Published
2019
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3. Identifications of Highly Aggressive Phenotype with SPI1 Overexpression in Pediatric T Cell Acute Lymphoblastic Leukemia/Lymphoma

Author

Seki, Masafumi, primary, Kimura, Shunsuke, additional, Yoshida, Kenichi, additional, Isobe, Tomoya, additional, Ueno, Hiroo, additional, Suzuki, Hiromichi, additional, Shiozawa, Yusuke, additional, Kataoka, Keisuke, additional, Fujii, Yoichi, additional, Shiraishi, Yuichi, additional, Chiba, Kenichi, additional, Tanaka, Hiroko, additional, Takagi, Masatoshi, additional, Iwama, Atsushi, additional, Oki, Kentaro, additional, Kato, Motohiro, additional, Koh, Katsuyoshi, additional, Hanada, Ryoji, additional, Moritake, Hiroshi, additional, Kobayashi, Ryoji, additional, Deguchi, Takao, additional, Hashii, Yoshiko, additional, Imamura, Toshihiko, additional, Sato, Atsushi, additional, Horibe, Keizo, additional, Kiyokawa, Nobutaka, additional, Manabe, Atsushi, additional, Ohara, Akira, additional, Sanada, Masashi, additional, Hayashi, Yasuhide, additional, Mano, Hiroyuki, additional, Miyano, Satoru, additional, Oka, Akira, additional, Ogawa, Seishi, additional, and Takita, Junko, additional

Published
2016
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4. Detection of Novel Pathogenic Gene Rearrangements in Pediatric Acute Myeloid Leukemia By RNA Sequencing

Author

Shiba, Norio, primary, Yoshida, Kenichi, additional, Shiraishi, Yuichi, additional, Hara, Yusuke, additional, Yamato, Genki, additional, Kaburaki, Taeko, additional, Sanada, Masashi, additional, Oki, Kentaro, additional, Tomizawa, Daisuke, additional, Sotomatsu, Manabu, additional, Arakawa, Hirokazu, additional, Horibe, Keizo, additional, PARK, Myoung-Ja, additional, Taga, Takashi, additional, Adachi, Souichi, additional, Tawa, Akio, additional, Miyano, Satoru, additional, Ogawa, Seishi, additional, and Hayashi, Yasuhide, additional

Published
2015
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5. RARB Translocations in Acute Promyelocytic Leukemia without Rara translocation

Author

Kato, Motohiro, Osumi, Tomoo, Tsujimoto, Shinichi, Tamura, Moe, Uchiyama, Meri, Nakabayashi, Kazuhiko, Okamura, Kohji, Tomizawa, Daisuke, Watanabe, Akihiro, Takahashi, Hiroyuki, Hori, Tsukasa, Yamamoto, Shohei, Hamamoto, Kazuko, Migita, Masahiro, Ogata-Kawata, Hiroko, Uchiyama, Toru, Kizawa, Hiroe, Ueno-Yokohata, Hitomi, Shirai, Ryota, Yoshida, Masanori, Seki, Masafumi, Oki, Kentaro, Takita, Junko, Ogawa, Seishi, Kitamura, Toshio, Matsumoto, Kimikazu, Hata, Kenichiro, Goyama, Susumu, and Kiyokawa, Nobutaka

Published
2017
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6. Poor Prognosis With Different Induction Rate Was Observed In Children With Acute Myeloid Leukemia and FLT3-ITD According To The ITD/WT Allelic Ratio: A Result From The Japanese Pediatric Leukemia/Lymphoma Study Group

Author

Shimada, Akira, primary, Yamashita, Yuka, additional, Tomizawa, Daisuke, additional, Tawa, Akio, additional, Watanabe, Tomoyuki, additional, Yokozawa, Toshiya, additional, Kudo, Kazuko, additional, Taga, Takashi, additional, Iwamoto, Shotaro, additional, Terui, Kiminori, additional, Moritake, Hiroshi, additional, Kinoshita, Akitoshi, additional, Takahashi, Hiroyuki, additional, Nakayama, Hideki, additional, Koh, Katsuyoshi, additional, Goto, Hiroaki, additional, Kosaka, Yoshiyuki, additional, Saito, Akiko Moriya, additional, Fujimoto, Junichiro, additional, Horibe, Keizo, additional, Oki, Kentaro, additional, Hayashi, Yasuhide, additional, and Adachi, Souichi, additional

Published
2013
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7. NUP98-NSD1 Fusion Gene Is Strongly Associated with a Poor Prognosis in Pediatric Acute Myeloid Leukemia: A Study of the Japanese Childhood AML99 Cooperative Study Group

Author

Shiba, Norio, primary, Taki, Tomohiko, additional, Park, Myoung-ja, additional, Murata, Chisato, additional, Oki, Kentaro, additional, Ichikawa, Hitoshi, additional, Shimada, Akira, additional, Kanazawa, Takashi, additional, Sotomatsu, Manabu, additional, Tabuchi, Ken, additional, Adachi, Souichi, additional, Tawa, Akio, additional, Horibe, Keizo, additional, Tsuchida, Masahiro, additional, Hanada, Ryoji, additional, Tsukimoto, Ichiro, additional, Arakawa, Hirokazu, additional, and Hayashi, Yasuhide, additional

Published
2011
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8. Mutational Analysis for IDH1 and IDH2 In Pediatric Leukemia

Author

Hiwatari, Mitsuteru, primary, Oki, Kentaro, additional, Takita, Jyunko, additional, Nishimura, Riki, additional, Sanada, Masashi, additional, Okubo, Jun, additional, Adachi, Masatoki, additional, Sotomatsu, Manabu, additional, Kikuchi, Akira, additional, Igarashi, Takashi, additional, Hayashi, Yasuhide, additional, and Ogawa, Seishi, additional

Published
2010
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9. Cord Blood Transplantation from Unrelated Donors for Children with Acute Lymphoblastic Leukemia in Japan: The Impact of Methotrexate on the Clinical Outcome.

Author

Kato, Koji, primary, Yoshimi, Ayami, primary, Ito, Etsuro, primary, Oki, Kentaro, primary, Hara, Jun, primary, Nagatoshi, Yoshihisa, primary, Kikuchi, Akira, primary, Kobayashi, Ryoji, primary, Nagamura-Inoue, Tokiko, primary, Kai, Shunro, primary, Azuma, Hiroshi, primary, Takanashi, Minoko, primary, Isoyama, Keiichi, primary, and Kato, Shunichi, primary

Published
2007
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10. RARBTranslocations in Acute Promyelocytic Leukemia without Raratranslocation

Author

Kato, Motohiro, Osumi, Tomoo, Tsujimoto, Shinichi, Tamura, Moe, Uchiyama, Meri, Nakabayashi, Kazuhiko, Okamura, Kohji, Tomizawa, Daisuke, Watanabe, Akihiro, Takahashi, Hiroyuki, Hori, Tsukasa, Yamamoto, Shohei, Hamamoto, Kazuko, Migita, Masahiro, Ogata-Kawata, Hiroko, Uchiyama, Toru, Kizawa, Hiroe, Ueno-Yokohata, Hitomi, Shirai, Ryota, Yoshida, Masanori, Seki, Masafumi, Oki, Kentaro, Takita, Junko, Ogawa, Seishi, Kitamura, Toshio, Matsumoto, Kimikazu, Hata, Kenichiro, Goyama, Susumu, and Kiyokawa, Nobutaka

Abstract

Introduction: Acute promyelocytic leukemia (APL) is defined by unique morphological features, typically abnormal promyelocytes containing azurophilic granules. Genomic basis of APL is characterized by the translocation t(15;17)(q22;q21), inducing fusions between promyelocytic leukemia (PML) and retinoic acid receptor-a (RARA). APL cells with PML-RARA respond to all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), and recent clinical trials have achieved excellent outcome for typical APL with PML-RARA. Although a certain fraction of APL cases lacks PMR-RARA, most of them had translocation including RARAand other genes, namely, PLZF, NPM, and TBL1XR1. Eventually, all known APL-associated translocations involve RARA, accounting for 99% of APL. However, RARArearrangement is unable to be detected in the rest of APL cases, and molecular mechanisms underlying this small subset is still unclear. We here analyzed APL cases without RARAtranslocation, and identified a novel RARBfusion in the majority of patients with RARA-negative APL.

Published
2017
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11. Identifications of Highly Aggressive Phenotype with SPI1Overexpression in Pediatric T Cell Acute Lymphoblastic Leukemia/Lymphoma

Author

Seki, Masafumi, Kimura, Shunsuke, Yoshida, Kenichi, Isobe, Tomoya, Ueno, Hiroo, Suzuki, Hiromichi, Shiozawa, Yusuke, Kataoka, Keisuke, Fujii, Yoichi, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Takagi, Masatoshi, Iwama, Atsushi, Oki, Kentaro, Kato, Motohiro, Koh, Katsuyoshi, Hanada, Ryoji, Moritake, Hiroshi, Kobayashi, Ryoji, Deguchi, Takao, Hashii, Yoshiko, Imamura, Toshihiko, Sato, Atsushi, Horibe, Keizo, Kiyokawa, Nobutaka, Manabe, Atsushi, Ohara, Akira, Sanada, Masashi, Hayashi, Yasuhide, Mano, Hiroyuki, Miyano, Satoru, Oka, Akira, Ogawa, Seishi, and Takita, Junko

Abstract

T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) accounts for 10% to 15% of newly diagnosed cases of childhood acute lymphoblastic leukemia (ALL), arising from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process. However, since the prognostic significance of these genetic alterations in pediatric T-ALL is not clear, genetic basis which contributes aggressive phenotype or progression of pediatric T-ALL is still to be elucidated. Therefore, to discover driver genetic events, which involved in the aggressive phenotype of pediatric T-ALL and to identify it's novel prognostic markers, we performed integrated genetic analysis in a large cohort of T-ALL case.

Published
2016
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12. NUP98-NSD1Fusion Gene Is Strongly Associated with a Poor Prognosis in Pediatric Acute Myeloid Leukemia: A Study of the Japanese Childhood AML99 Cooperative Study Group

Author

Shiba, Norio, Taki, Tomohiko, Park, Myoung-ja, Murata, Chisato, Oki, Kentaro, Ichikawa, Hitoshi, Shimada, Akira, Kanazawa, Takashi, Sotomatsu, Manabu, Tabuchi, Ken, Adachi, Souichi, Tawa, Akio, Horibe, Keizo, Tsuchida, Masahiro, Hanada, Ryoji, Tsukimoto, Ichiro, Arakawa, Hirokazu, and Hayashi, Yasuhide

Abstract

Abstract 1475

Published
2011
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