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25 results on '"Ness, Kirsten K."'

3. Epigenetic Age Acceleration and Neurocognitive Function Among Long-Term Survivors of Pediatric Hodgkin Lymphoma: A Report from the St. Jude Lifetime Cohort

Author

Williams, AnnaLynn M, primary, Dong, Qian, additional, Phillips, Nicholas S., additional, Ehrhardt, Matt J., additional, Srivastava, Deokumar, additional, Mirzaei Salehabadi, Sedigheh, additional, Yasui, Yutaka, additional, Ness, Kirsten K., additional, Hudson, Melissa M., additional, Robison, Leslie L., additional, Krull, Kevin R., additional, and Wang, Zhaoming, additional

Published
2022
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10. Chronic Health Conditions and Late Mortality Among Survivors of Childhood Acute Myeloid Leukemia: A Report from the Childhood Cancer Survivor Study (CCSS)

Author

Turcotte, Lucie M, primary, Whitton, John A, additional, Leisenring, Wendy M., additional, Gibson, Todd, additional, Howell, Rebecca M, additional, Krull, Kevin R., additional, Neglia, Joseph P., additional, Oeffinger, Kevin C, additional, Ness, Kirsten K., additional, Woods, William G., additional, Kolb, E. Anders, additional, Robison, Leslie L., additional, Armstrong, Gregory T, additional, and Chow, Eric J, additional

Published
2019
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12. Estimated Late Health Outcomes in Children Newly Diagnosed with Mature B-Cell Non-Hodgkin Lymphoma Treated with Contemporary LMB Chemotherapy Based upon Similarly Treated Participants in the Childhood Cancer Survivor Study (CCSS)

Author

Ehrhardt, Matthew J., primary, Chen, Yan, additional, Sandlund, John, additional, Bluhm, Elizabeth C., additional, Hayashi, Robert J., additional, Leisenring, Wendy M., additional, Metzger, Monika L., additional, Ness, Kirsten K., additional, Krull, Kevin R., additional, Oeffinger, Kevin C., additional, Robison, Leslie L., additional, Yasui, Yutaka, additional, Armstrong, Gregory T., additional, Hudson, Melissa M., additional, and Mulrooney, Daniel A., additional

Published
2016
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13. Association Between Chronic Pulmonary Conditions and Neurocognitive Function in Long-Term Survivors of Childhood Hodgkin Lymphoma

Author

Cheung, Yin Ting, primary, Sabin, Noah D., additional, Mulrooney, Daniel A., additional, Ness, Kirsten K., additional, Krasin, Matthew J, additional, Brinkman, Tara M., additional, Banerjee, Pia, additional, Srivastava, Deokumar, additional, Robison, Leslie L., additional, Hudson, Melissa M., additional, and Krull, Kevin R., additional

Published
2016
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14. Neurocognitive, Psychosocial, and Quality of Life Outcomes in Adult Survivors of Childhood Non-Hodgkin Lymphoma in the St. Jude Lifetime (SJLIFE) Cohort

Author

Ehrhardt, Matthew J., primary, Mulrooney, Daniel A., additional, Li, Chenghong, additional, Sandlund, John T., additional, Brinkman, Tara M., additional, Huang, I-Chan, additional, Srivastava, DeoKumar, additional, Ness, Kirsten K., additional, Robison, Leslie L., additional, Hudson, Melissa M., additional, and Krull, Kevin R., additional

Published
2015
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15. Physiologic Frailty Among Hematopoietic Cell Transplantation (HCT) Survivors Suggests Accelerated Aging and Is a Predictor for Premature Mortality: A Report from the Bone Marrow Transplant Survivor Study (BMTSS)

Author

Arora, Mukta, primary, Sun, Can-Lan, additional, Ness, Kirsten K., additional, Teh, Jennifer Berano, additional, Wu, Jessica, additional, Francisco, Liton F., additional, Armenian, Saro, additional, Schad, Amy, additional, Namdar, Golnaz, additional, Bosworth, Alysia, additional, Kuo, Linus, additional, Weisdorf, Daniel, additional, Forman, Stephen J., additional, and Bhatia, Smita, additional

Published
2015
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16. Late Outcomes of Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL) Diagnosed Between 1963-2002: A Report from the St. Jude Lifetime (SJLIFE) Cohort Study

Author

Mulrooney, Daniel A., primary, Jones, Kendra E., additional, Ness, Kirsten K., additional, Crom, Deborah B., additional, Ehrhardt, Matthew J., additional, Brinkman, Tara M., additional, Krull, Kevin R., additional, Chemaitilly, Wassim, additional, Kun, Larry E., additional, Kaste, Sue C., additional, Armstrong, Gregory T., additional, Srivastava, Deokumar, additional, Relling, Mary V., additional, Pui, Ching-Hon, additional, Jeha, Sima, additional, Sandlund, John T., additional, Green, Daniel M., additional, Robison, Leslie L., additional, and Hudson, Melissa M., additional

Published
2014
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17. Longitudinal Evaluation Of Health Status In Aging Pediatric Hodgkin Lymphoma Survivors: Report From The Childhood Cancer Survivor Study

Author

Effinger, Karen E., primary, Leisenring, Wendy M., additional, Oeffinger, Kevin C., additional, Hudson, Melissa M., additional, Ness, Kirsten K., additional, Marina, Neyssa, additional, Stovall, Marilyn, additional, Armstrong, Gregory T., additional, Robison, Leslie L., additional, Sainani, Kristin, additional, and Whittemore, Alice S., additional

Published
2013
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20. Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study

Author

Scott Baker, K., primary, Ness, Kirsten K., additional, Steinberger, Julia, additional, Carter, Andrea, additional, Francisco, Liton, additional, Burns, Linda J., additional, Sklar, Charles, additional, Forman, Stephen, additional, Weisdorf, Daniel, additional, Gurney, James G., additional, and Bhatia, Smita, additional

Published
2006
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22. Functional Limitations, Physical Disability and Social Competence among HCT Survivors Transplanted during Childhood or Adolescence: A Report from the Bone Marrow Transplant Survivor Study.

Author

Ness, Kirsten K., primary, Gurney, James G., additional, Baker, K. S., additional, Francisco, Liton, additional, Carter, Andrea, additional, Forman, Stephen J., additional, Robison, Leslie L., additional, Rosenthal, Joseph, additional, and Bhatia, Smita, additional

Published
2004
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23. Chronic conditions, late mortality, and health status after childhood AML: a Childhood Cancer Survivor Study report

Author

Turcotte, Lucie M., Whitton, Jillian A., Leisenring, Wendy M., Howell, Rebecca M., Neglia, Joseph P., Phelan, Rachel, Oeffinger, Kevin C., Ness, Kirsten K., Woods, William G., Kolb, E. Anders, Robison, Leslie L., Armstrong, Gregory T., and Chow, Eric J.

Abstract

Five-year survival following childhood acute myeloid leukemia (AML) has increased following improvements in treatment and supportive care. Long-term health outcomes are unknown. To address this, cumulative incidence of late mortality and grades 3 to 5 chronic health condition (CHC) were estimated among 5-year AML survivors diagnosed between 1970 and 1999. Survivors were compared by treatment group (hematopoietic cell transplantation [HCT], chemotherapy with cranial radiation [chemo + CRT], chemotherapy only [chemo-only]), and diagnosis decade. Self-reported health status was compared across treatments, diagnosis decade, and with siblings. Among 856 survivors (median diagnosis age, 7.1 years; median age at last follow-up, 29.4 years), 20-year late mortality cumulative incidence was highest after HCT (13.9%; 95% confidence interval [CI], 10.0%-17.8%; chemo + CRT, 7.6%; 95% CI, 2.2%-13.1%; chemo-only, 5.1%; 95% CI, 2.8%-7.4%). Cumulative incidence of mortality for HCT survivors diagnosed in the 1990s (8.5%; 95% CI, 4.1%-12.8%) was lower vs those diagnosed in the 1970s (38.9%; 95% CI, 16.4%-61.4%). Most survivors did not experience any grade 3 to 5 CHC after 20 years (HCT, 45.8%; chemo + CRT, 23.7%; chemo-only, 27.0%). Furthermore, a temporal reduction in CHC cumulative incidence was seen after HCT (1970s, 76.1%; 1990s, 38.3%; P= .02), mirroring reduced use of total body irradiation. Self-reported health status was good to excellent for 88.2% of survivors; however, this was lower than that for siblings (94.8%; P< .0001). Although HCT is associated with greater long-term morbidity and mortality than chemotherapy-based treatment, gaps have narrowed, and all treatment groups report favorable health status.

Published
2022
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24. Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study

Author

Scott Baker, K., Ness, Kirsten K., Steinberger, Julia, Carter, Andrea, Francisco, Liton, Burns, Linda J., Sklar, Charles, Forman, Stephen, Weisdorf, Daniel, Gurney, James G., and Bhatia, Smita

Abstract

We ascertained the prevalence of self-reported late occurrence of diabetes, hypertension, and cardiovascular (CV) disease in 1089 hematopoietic cell transplantation (HCT) survivors who underwent HCT between 1974 and 1998, survived at least 2 years, and were not currently taking immunosuppressant agents and compared them with 383 sibling controls. All subjects completed a 255-item health questionnaire. The mean age at survey completion was 39.3 years for survivors and 38.6 years for siblings; mean follow-up was 8.6 years. Adjusting for age, sex, race, and body mass index (BMI), survivors of allogeneic HCT were 3.65 times (95% confidence interval [CI], 1.82-7.32) more likely to report diabetes than siblings and 2.06 times (95% CI, 1.39-3.04) more likely to report hypertension compared with siblings but did not report other CV outcomes with any greater frequency. Recipients of autologous HCTs were no more likely than siblings to report any of the outcomes studied. Allogeneic HCT survivors were also more likely to develop hypertension (odds ratio [OR] = 2.31; 95% CI, 1.45-3.67) than autologous recipients. Total body irradiation (TBI) exposure was associated with an increased risk of diabetes (OR = 3.42; 95% CI, 1.55-7.52). Thus, HCT survivors have a higher age- and BMI-adjusted risk of diabetes and hypertension, potentially leading to a higher than expected risk of CV events with age.

Published
2007
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25. Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study.

Author

Baker KS, Ness KK, Steinberger J, Carter A, Francisco L, Burns LJ, Sklar C, Forman S, Weisdorf D, Gurney JG, and Bhatia S

Subjects
Adult, Cardiovascular Diseases epidemiology, Case-Control Studies, Data Collection, Diabetes Mellitus epidemiology, Follow-Up Studies, Humans, Hypertension epidemiology, Prevalence, Siblings, Survivors, Transplantation, Autologous, Transplantation, Homologous, Whole-Body Irradiation adverse effects, Cardiovascular Diseases etiology, Diabetes Mellitus etiology, Hematopoietic Stem Cell Transplantation adverse effects, Hypertension etiology
Abstract

We ascertained the prevalence of self-reported late occurrence of diabetes, hypertension, and cardiovascular (CV) disease in 1089 hematopoietic cell transplantation (HCT) survivors who underwent HCT between 1974 and 1998, survived at least 2 years, and were not currently taking immunosuppressant agents and compared them with 383 sibling controls. All subjects completed a 255-item health questionnaire. The mean age at survey completion was 39.3 years for survivors and 38.6 years for siblings; mean follow-up was 8.6 years. Adjusting for age, sex, race, and body mass index (BMI), survivors of allogeneic HCT were 3.65 times (95% confidence interval [CI], 1.82-7.32) more likely to report diabetes than siblings and 2.06 times (95% CI, 1.39-3.04) more likely to report hypertension compared with siblings but did not report other CV outcomes with any greater frequency. Recipients of autologous HCTs were no more likely than siblings to report any of the outcomes studied. Allogeneic HCT survivors were also more likely to develop hypertension (odds ratio [OR]=2.31; 95% CI, 1.45-3.67) than autologous recipients. Total body irradiation (TBI) exposure was associated with an increased risk of diabetes (OR=3.42; 95% CI, 1.55-7.52). Thus, HCT survivors have a higher age- and BMI-adjusted risk of diabetes and hypertension, potentially leading to a higher than expected risk of CV events with age.

Published
2007
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