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3 results on '"Li, Jinggang"'

1. Lncrna Famlf-2 Promotes Leukemogenesis Via the DHX9/c-Myc Axis in Acute Lymphoblastic Leukemia

Author

Lai, Xiaolin, primary, Cai, Yuanhua, additional, Huang, Yuanmao, additional, Shi, Shuiling, additional, Chen, Zhixiang, additional, Wang, Xuechun, additional, Tu, Fuquan, additional, Ye, Luya, additional, Li, Xiaofan, additional, PAN, Lili, additional, Li, Jinggang, additional, Li, Yang, additional, Gao, Huiying, additional, and Wang, Shaoyuan, additional

Published
2023
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3. Lncrna Famlf-2Promotes Leukemogenesis Via the DHX9/c-Myc Axis in Acute Lymphoblastic Leukemia

Author

Lai, Xiaolin, Cai, Yuanhua, Huang, Yuanmao, Shi, Shuiling, Chen, Zhixiang, Wang, Xuechun, Tu, Fuquan, Ye, Luya, Li, Xiaofan, PAN, Lili, Li, Jinggang, Li, Yang, Gao, Huiying, and Wang, Shaoyuan

Abstract

Long noncoding RNAs (lncRNAs), defined as the transcripts longer than 200 nt without protein-coding capacity, have been found to be aberrantly expressed in diverse human diseases including leukemia. Our previous study identified Familial acute myelogenous leukemia related factor ( FAMLF) in an acute myeloblastic leukemia (AML) pedigree. Two splice variants of FAMLF, FAMLF-1 and FAMLF-2were detected. FAMLF-1 is upgraded in AML patients and associated with poor prognosis. However, the full cDNA sequence of FAMLF-2is not verified and its role in leukemogenesis remain unclear. Herein, we aim to investigate the functional and mechanistic roles of FAMLF-2in leukemia.

Published
2023
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