49 results on '"Lee, Stanley"'
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2. Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML
3. Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2
4. MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development
5. Therapeutic Targeting of Spliceosome Mutant Myeloid Neoplasms Via PARP1 Inhibition
6. Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma
7. Spliceosome Mutant Myeloid Malignancies Are Preferentially Sensitive to PARP Inhibition
8. Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias
9. Aberrant RNA Splicing Contributes to the Pathogenesis of EVI-Rearranged Myeloid Leukemias
10. Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling
11. Therapeutic Targeting of an RNA Splicing Factor Network for the Treatment of Myeloid Neoplasms
12. Multimodal Single-Cell Profiling Defines the Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution
13. Mutations in the RNA Splicing Factor SF3B1 Promote Transformation through MYC Stabilization
14. Integrated Molecular Analysis Identifies Replicative Stress As Sensitizer to Imetelstat Therapy in AML
15. Oncogenic Mutations in XPO1 Promote Lymphoid Transformation By Altering Nuclear/Cytoplasmic Localization of NFκB Signaling Intermediates
16. Inhibiting the Nuclear Exporter XPO1 and the Antiapoptotic Factor BCL2 Is Synergistic in XPO1 Mutant and Wildtype Lymphoma
17. Recurrent CDKN1B (p27) mutations in hairy cell leukemia
18. Modeling CBL activating mutations in vivo
19. H3B-8800, an Orally Bioavailable Modulator of the SF3b Complex, Shows Efficacy in Spliceosome-Mutant Myeloid Malignancies
20. Synthetic Lethal Interactions of MDS-Associated Spliceosomal Gene Mutations Identifies the Basis for Their Mutual Exclusivity
21. Serine/Arginine-Rich Splicing Factor 1 (SRSF1) Is Required for Adult and Embryonic Hematopoiesis and Has Non-Overlapping Roles with SRSF2 in Hematopoiesis
22. The Preclinical Efficacy of a Novel Telomerase Inhibitor, Imetelstat, in AML - a Randomized Trial in Patient-Derived Xenografts
23. Aberrant EVI1splicing contributes to EVI1-rearranged leukemia
24. Multi-Omics Analysis Reveals That TET2 Loss Epigenetically Primes Monocytes for Inflammatory Responses Via AP-1 Signaling
25. Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms
26. Therapeutic Targeting of Spliceosomal Mutant Myeloid Leukemias through Modulation of Splicing Catalysis
27. ASXL2 Is a Novel Mediator of RUNX1-ETO Transcriptional Function and Collaborates with RUNX1-ETO to Promote Leukemogenesis
28. Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation
29. Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis
30. Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis
31. SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference
32. Modeling CBL activating mutations in vivo.
33. Recurrent CDKN1B(p27) mutations in hairy cell leukemia
34. MOZ regulates B-cell progenitors and, consequently, Mozhaploinsufficiency dramatically retards MYC-induced lymphoma development
35. Modeling CBLactivating mutations in vivo
36. Leukemia in Fanconi’s Anemia: Cytogenetic and Tumor Virus Susceptibility Studies
37. Endocrine Relationships of Leukocyte Alkaline Phosphatase
38. Studies of Leukocyte Alkaline Phosphatase in Mongolism: A Possible Chromosome Marker
39. The Effectiveness of Combinations of Antileukemic Agents in Inducing and Maintaining Remission in Children with Acute Leukemia
40. Inhibition of Leukocyte Agglutination by Serum from Patients with Systemic Lupus Erythematosus: A Manifestation of the L.E. Cell Phenomenon
41. Immunofluorescent Studies of Human Leukemic Cells with Antiserum to a Murine Leukemic Virus (Rauscher Strain)
42. The Effect of 6-Mercaptopurine on the Duration of Steroid-induced Remissions in Acute Leukemia: A Model for Evaluation of Other Potentially Useful Therapy
43. Blood Coagulation and the L. E. Cell Phenomenon
44. Studies of Leukocyte Alkaline Phosphatase in Mongolism: A Possible Chromosome Marker
45. Oncogenic Mutations in XPO1Promote Lymphoid Transformation By Altering Nuclear/Cytoplasmic Localization of NFκB Signaling Intermediates
46. Spliceosomal Dysfunction Is a Critical Mediator of IDH2Mutant Leukemogenesis
47. SRSF2Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference
48. Histiocytic Lymphoma Fifteen Years Following Remission of Acute Lymphoblastic Leukemia
49. Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML.
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