Search

Your search keyword '"Ferrara, Leonardo"' showing total 5 results
Start Over Author "Ferrara, Leonardo" Journal blood
5 results on '"Ferrara, Leonardo"'

5. Helicobacter pylorieradication can induce platelet recovery in idiopathic thrombocytopenic purpura

Author

Emilia, Giovanni, Longo, Giuseppe, Luppi, Mario, Gandini, Giovanna, Morselli, Monica, Ferrara, Leonardo, Amarri, Sergio, Cagossi, Katia, and Torelli, Giuseppe

Abstract

Recent reports have suggested an association betweenHelicobacter pyloriinfection and idiopathic thrombocytopenic purpura (ITP). The prevalence of H pyloriinfection and the effect of its eradication in a series of 30 ITP patients were investigated. H pyloriinfection has been documented in 13 patients (43.33%) by 13C urea breath test and confirmed by histologic examination. Bacterium eradication with antibiotics, obtained in 12 of 13 infected patients (92.3%), led to a complete response in 4 (33.33%) and to a partial response (platelets 90 × 109/L-120 × 109/L) in 2 (16.66%). The response was maintained for a median of 8.33 months, but 1 patient relapsed 7 months after eradication. Search for H pyloriinfection seems appropriate in ITP patients at diagnosis. Bacterium eradication provides a new good option for a nonimmunosuppressive treatment in some ITP patients.

Published
2001
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results