180 results on '"Denis, Cécile V."'
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2. How unique structural adaptations support and coordinate the complex function of von Willebrand factor
3. Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models
4. A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD
5. Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
6. Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity
7. The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction
8. Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
9. A mutation of the human EPHB2 gene leads to a major platelet functional defect
10. Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?
11. Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions
12. Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X
13. Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice
14. von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends
15. Accelerated uptake of VWF/platelet complexes in macrophages contributes to VWD type 2B–associated thrombocytopenia
16. Mutations in the A3 domain of Von Willebrand factor inducing combined qualitative and quantitative defects in the protein
17. A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor
18. Macrophage LRP1 contributes to the clearance of von Willebrand factor
19. Mutation and ADAMTS13-dependent modulation of disease severity in a mouse model for von Willebrand disease type 2B
20. von Willebrand disease: what does the future hold?
21. Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo
22. Altered thrombus formation in von Willebrand factor–deficient mice expressing von Willebrand factor variants with defective binding to collagen or GPIIbIIIa
23. A hemophilia A mouse model for the in vivo assessment of emicizumab function
24. Von Willebrand factor C1C2 domain is involved in platelet adhesion to polymerized fibrin at high shear rate
25. A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation
26. Localized reduction of atherosclerosis in von Willebrand factor–deficient mice
27. Von Willebrand factor: how unique structural adaptations support and coordinate its complex function
28. VWF clearance: it’s glycomplicated
29. Pas de deux between VWF and ADAMTS13
30. Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate
31. The Von Willebrand Factor Tyr2561 Allele Is a Gain-of-Function Variant and a Potential Risk Factor for Early Myocardial Infarction
32. A mutation of the human EPHB2gene leads to a major platelet functional defect
33. Platelet Desialylation Is a Novel Mechanism of Thrombocytopenia during Mechanical Circulatory Assistance
34. Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm
35. Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice
36. GpIbα-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice
37. Platelet von Willebrand factor: sweet resistance
38. Determinants of von Willebrand Factor Function
39. Mechanisms and Therapeutic Modulation of the Bleeding Tendency in Genetically-Engineered Von Willebrand Disease Type 2B Mice
40. A nanobody against the von Willebrand factor A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired von Willebrand disease
41. Siglecs as Novel Cellular Partners for Von Willebrand Factor
42. Correction of the bleeding time in von Willebrand factor (VWF)–deficient mice using murine VWF
43. O-Linked Glycosylation with Sialylated T-Antigen: A Novel Carbohydrate Determinant of von Willebrand Factor Antigen Levels.
44. Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels
45. Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models
46. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins
47. Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpurain mice
48. Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels
49. Pas de deuxbetween VWF and ADAMTS13
50. Hemostatic disorders in a JAK2V617F -driven mouse model of myeloproliferative neoplasm.
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