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1. High Progression Free Survival Rates in Patients with Multiply Relapsed/Refractory Hodgkin Lymphoma Undergoing Autologous Stem Cell Transplant after Checkpoint Inhibitors: Results from Grupo Argentino De Trasplante De Medula Osea y Terapia Celular (GATMO-TC)

Author

Korin, Laura, Castro, Martin, Palmer, Silvina, Sardu, Lautaro, Basquiera, Ana, Yantorno, Sebastian, Jarchum, Sol, Figueroa, Maria Flavia Flavia, Colucci, Magali, Funes, María Eugenia, Bentolila, Gonzalo, Saslavsky, Martin, Banchieri, Alejandra, Rosales Ostriz, Maria Belén, Penalba, Romina, Quarchione, Micaela, Jaimovich, Gregorio, Milone, Gustavo, Vitriu, Adriana, and Foncuberta, Maria Cecilia

Abstract

Consolidation with autologous stem cell transplant (ASCT) in Hodgkin lymphoma (HL) was traditionally reserved for patients with chemosensitive disease. In 2021 a retrospective study showed encouraging results with ASCT consolidation after checkpoint inhibitors (CPI) in pts with relapsed/refractory (R/R) HL. Subsequently, several prospective studies with CPI +/- chemotherapy in 2nd line were published showing 1-year progression free survival (1-y PFS) rates of 90% but with increased incidence of engrafment syndrome.

Published
2023
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