4 results on '"Stamm, Thomas"'
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2. Efficacy of cognitive‐behavioral group therapy in patients at risk for serious mental illness presenting with subthreshold bipolar symptoms: Results from a prespecified interim analysis of a multicenter, randomized, controlled study
- Author
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Leopold, Karolina, primary, Bauer, Michael, additional, Bechdolf, Andreas, additional, Correll, Christoph U., additional, Holtmann, Martin, additional, Juckel, Georg, additional, Lambert, Martin, additional, Meyer, Thomas D., additional, Pfeiffer, Steffi, additional, Kittel‐Schneider, Sarah, additional, Reif, Andreas, additional, Stamm, Thomas J., additional, Rottmann‐Wolf, Maren, additional, Mathiebe, Josephine, additional, Kellmann, Eva L., additional, Ritter, Philipp, additional, Krüger‐Özgürdal, Seza, additional, Karow, Anne, additional, Sondergeld, Lene‐Marie, additional, Roessner, Veit, additional, Sauer, Cathrin, additional, and Pfennig, Andrea, additional
- Published
- 2020
- Full Text
- View/download PDF
3. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study
- Author
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Kalman, Janos L, primary, Papiol, Sergi, additional, Forstner, Andreas J, additional, Heilbronner, Urs, additional, Degenhardt, Franziska, additional, Strohmaier, Jana, additional, Adli, Mazda, additional, Adorjan, Kristina, additional, Akula, Nirmala, additional, Alda, Martin, additional, Anderson‐Schmidt, Heike, additional, Andlauer, Till FM, additional, Anghelescu, Ion‐George, additional, Ardau, Raffaella, additional, Arias, Bárbara, additional, Arolt, Volker, additional, Aubry, Jean‐Michel, additional, Backlund, Lena, additional, Bartholdi, Kim, additional, Bauer, Michael, additional, Baune, Bernhard T, additional, Becker, Thomas, additional, Bellivier, Frank, additional, Benabarre, Antonio, additional, Bengesser, Susanne, additional, Bhattacharjee, Abesh Kumar, additional, Biernacka, Joanna M, additional, Birner, Armin, additional, Brichant‐Petitjean, Clara, additional, Budde, Monika, additional, Cervantes, Pablo, additional, Chillotti, Caterina, additional, Cichon, Sven, additional, Clark, Scott R, additional, Colom, Francesc, additional, Comes, Ashley L, additional, Cruceanu, Cristiana, additional, Czerski, Piotr M, additional, Dannlowski, Udo, additional, Dayer, Alexandre, additional, Del Zompo, Maria, additional, DePaulo, Jay Raymond, additional, Dietrich, Detlef E, additional, Étain, Bruno, additional, Ethofer, Thomas, additional, Falkai, Peter, additional, Fallgatter, Andreas, additional, Figge, Christian, additional, Flatau, Laura, additional, Folkerts, Here, additional, Frisen, Louise, additional, Frye, Mark A, additional, Fullerton, Janice M, additional, Gade, Katrin, additional, Gard, Sébastien, additional, Garnham, Julie S, additional, Goes, Fernando S, additional, Grigoroiu‐Serbanescu, Maria, additional, Gryaznova, Anna, additional, Hake, Maria, additional, Hauser, Joanna, additional, Herms, Stefan, additional, Hoffmann, Per, additional, Hou, Liping, additional, Jäger, Markus, additional, Jamain, Stephane, additional, Jiménez, Esther, additional, Juckel, Georg, additional, Kahn, Jean‐Pierre, additional, Kassem, Layla, additional, Kelsoe, John, additional, Kittel‐Schneider, Sarah, additional, Kliwicki, Sebastian, additional, Klohn‐Sagatholislam, Farah, additional, Koller, Manfred, additional, König, Barbara, additional, Konrad, Carsten, additional, Lackner, Nina, additional, Laje, Gonzalo, additional, Landén, Mikael, additional, Lang, Fabian U, additional, Lavebratt, Catharina, additional, Leboyer, Marion, additional, Leckband, Susan G, additional, Maj, Mario, additional, Manchia, Mirko, additional, Martinsson, Lina, additional, McCarthy, Michael J, additional, McElroy, Susan L, additional, McMahon, Francis J, additional, Mitchell, Philip B, additional, Mitjans, Marina, additional, Mondimore, Francis M, additional, Monteleone, Palmiero, additional, Nieratschker, Vanessa, additional, Nievergelt, Caroline M, additional, Novák, Tomas, additional, Ösby, Urban, additional, Pfennig, Andrea, additional, Potash, James B, additional, Reich‐Erkelenz, Daniela, additional, Reif, Andreas, additional, Reimer, Jens, additional, Reininghaus, Eva, additional, Reitt, Markus, additional, Ripke, Stephan, additional, Rouleau, Guy A, additional, Rybakowski, Janusz K, additional, Schalling, Martin, additional, Scherk, Harald, additional, Schmauß, Max, additional, Schofield, Peter R, additional, Schubert, K Oliver, additional, Schulte, Eva C, additional, Schulz, Sybille, additional, Senner, Fanny, additional, Severino, Giovanni, additional, Shekhtman, Tatyana, additional, Shilling, Paul D, additional, Simhandl, Christian, additional, Slaney, Claire M, additional, Spitzer, Carsten, additional, Squassina, Alessio, additional, Stamm, Thomas, additional, Stegmaier, Sophia, additional, Stierl, Sebastian, additional, Stopkova, Pavla, additional, Thiel, Andreas, additional, Tighe, Sarah K, additional, Tortorella, Alfonso, additional, Turecki, Gustavo, additional, Vieta, Eduard, additional, Veeh, Julia, additional, von Hagen, Martin, additional, Wigand, Moritz E, additional, Wiltfang, Jens, additional, Witt, Stephanie, additional, Wright, Adam, additional, Zandi, Peter P, additional, Zimmermann, Jörg, additional, Nöthen, Markus, additional, Rietschel, Marcella, additional, and Schulze, Thomas G, additional
- Published
- 2018
- Full Text
- View/download PDF
4. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.
- Author
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Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M, Anderson-Schmidt H, Andlauer TF, Anghelescu IG, Ardau R, Arias B, Arolt V, Aubry JM, Backlund L, Bartholdi K, Bauer M, Baune BT, Becker T, Bellivier F, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Brichant-Petitjean C, Budde M, Cervantes P, Chillotti C, Cichon S, Clark SR, Colom F, Comes AL, Cruceanu C, Czerski PM, Dannlowski U, Dayer A, Del Zompo M, DePaulo JR, Dietrich DE, Étain B, Ethofer T, Falkai P, Fallgatter A, Figge C, Flatau L, Folkerts H, Frisen L, Frye MA, Fullerton JM, Gade K, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Gryaznova A, Hake M, Hauser J, Herms S, Hoffmann P, Hou L, Jäger M, Jamain S, Jiménez E, Juckel G, Kahn JP, Kassem L, Kelsoe J, Kittel-Schneider S, Kliwicki S, Klohn-Sagatholislam F, Koller M, König B, Konrad C, Lackner N, Laje G, Landén M, Lang FU, Lavebratt C, Leboyer M, Leckband SG, Maj M, Manchia M, Martinsson L, McCarthy MJ, McElroy SL, McMahon FJ, Mitchell PB, Mitjans M, Mondimore FM, Monteleone P, Nieratschker V, Nievergelt CM, Novák T, Ösby U, Pfennig A, Potash JB, Reich-Erkelenz D, Reif A, Reimer J, Reininghaus E, Reitt M, Ripke S, Rouleau GA, Rybakowski JK, Schalling M, Scherk H, Schmauß M, Schofield PR, Schubert KO, Schulte EC, Schulz S, Senner F, Severino G, Shekhtman T, Shilling PD, Simhandl C, Slaney CM, Spitzer C, Squassina A, Stamm T, Stegmaier S, Stierl S, Stopkova P, Thiel A, Tighe SK, Tortorella A, Turecki G, Vieta E, Veeh J, von Hagen M, Wigand ME, Wiltfang J, Witt S, Wright A, Zandi PP, Zimmermann J, Nöthen M, Rietschel M, and Schulze TG
- Subjects
- Adolescent, Adult, Age Factors, Child, Female, Humans, Male, Middle Aged, Multifactorial Inheritance, Phenotype, Bipolar Disorder genetics, Schizophrenia genetics
- Abstract
Objectives: Bipolar disorder (BD) with early disease onset is associated with an unfavorable clinical outcome and constitutes a clinically and biologically homogenous subgroup within the heterogeneous BD spectrum. Previous studies have found an accumulation of early age at onset (AAO) in BD families and have therefore hypothesized that there is a larger genetic contribution to the early-onset cases than to late onset BD. To investigate the genetic background of this subphenotype, we evaluated whether an increased polygenic burden of BD- and schizophrenia (SCZ)-associated risk variants is associated with an earlier AAO in BD patients., Methods: A total of 1995 BD type 1 patients from the Consortium of Lithium Genetics (ConLiGen), PsyCourse and Bonn-Mannheim samples were genotyped and their BD and SCZ polygenic risk scores (PRSs) were calculated using the summary statistics of the Psychiatric Genomics Consortium as a training data set. AAO was either separated into onset groups of clinical interest (childhood and adolescence [≤18 years] vs adulthood [>18 years]) or considered as a continuous measure. The associations between BD- and SCZ-PRSs and AAO were evaluated with regression models., Results: BD- and SCZ-PRSs were not significantly associated with age at disease onset. Results remained the same when analyses were stratified by site of recruitment., Conclusions: The current study is the largest conducted so far to investigate the association between the cumulative BD and SCZ polygenic risk and AAO in BD patients. The reported negative results suggest that such a polygenic influence, if there is any, is not large, and highlight the importance of conducting further, larger scale studies to obtain more information on the genetic architecture of this clinically relevant phenotype., (© 2018 The Authors. Bipolar Disorders Published by John Wiley & Sons Ltd.)
- Published
- 2019
- Full Text
- View/download PDF
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