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1. Efficacy and safety of established and off‐label ADHD drug therapies for cognitive impairment or attention‐deficit hyperactivity disorder symptoms in bipolar disorder: A systematic review by the ISBD Targeting Cognition Task Force

Author

Miskowiak, Kamilla W., primary, Obel, Zacharias K., additional, Gugliemo, Riccardo, additional, Bonnin, Caterina del Mar, additional, Bowie, Christopher R., additional, Balanzá‐Martínez, Vicente, additional, Burdick, Katherine E., additional, Carvalho, Andre F., additional, Dols, Annemieke, additional, Douglas, Katie, additional, Gallagher, Peter, additional, Kessing, Lars V., additional, Lafer, Beny, additional, Lewandowski, Kathryn E., additional, López‐Jaramillo, Carlos, additional, Martinez‐Aran, Anabel, additional, McIntyre, Roger S., additional, Porter, Richard J., additional, Purdon, Scot E., additional, Schaffer, Ayal, additional, Stokes, Paul R. A., additional, Sumiyoshi, Tomiki, additional, Torres, Ivan J., additional, Van Rheenen, Tamsyn E., additional, Yatham, Lakshmi N., additional, Young, Allan H., additional, Vieta, Eduard, additional, and Hasler, Gregor, additional

Published
2024
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2. Essential data dimensions for prospective international data collection in older age bipolar disorder (OABD): Recommendations from the GAGE-BD group.

Author

Lavin, Paola, Rej, Soham, Olagunju, Andrew T., Teixeira, Antonio L., Dols, Annemieke, Alda, Martin, Almeida, Osvaldo P., Altinbas, Kursat, Balanzá-Martínez, Vicent, Barbosa, Izabela G., Blumberg, Hilary P., Briggs, Farren, Calkin, Cynthia, Cassidy, Kristin, Forester, Brent P., Forlenza, Orestes V., Hajek, Tomas, Haarman, Barthomeus C. M., Jimenez, Esther, and Lafer, Beny

Subjects
BIPOLAR disorder, ACQUISITION of data, DELPHI method, MENTAL depression, RESEARCH questions, GERIATRIC psychiatry, HYPOMANIA
Abstract

Background: By 2030, over 50% of individuals living with bipolar disorder (BD) are expected to be aged ≥50 years. However, older age bipolar disorder (OABD) remains understudied. There are limited large-scale prospectively collected data organized in key dimensions capable of addressing several fundamental questions about BD affecting this subgroup of patients. Methods: We developed initial recommendations for the essential dimensions for OABD data collection, based on (1) a systematic review of measures used in OABD studies, (2) a Delphi consensus of international OABD experts, (3) experience with harmonizing OABD data in the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE-BD, n ≥ 4500 participants), and (4) critical feedback from 34 global experts in geriatric mental health. Results: We identified 15 key dimensions and variables within each that are relevant for the investigation of OABD: (1) demographics, (2) core symptoms of depression and (3) mania, (4) cognition screening and subjective cognitive function, (5) elements for BD diagnosis, (6) descriptors of course of illness, (7) treatment, (8) suicidality, (9) current medication, (10) psychiatric comorbidity, (11) psychotic symptoms, (12) general medical comorbidities, (13) functioning, (14) family history, and (15) other. We also recommend particular instruments for capturing some of the dimensions and variables. Conclusion: The essential data dimensions we present should be of use to guide future international data collection in OABD and clinical practice. In the longer term, we aim to establish a prospective consortium using this core set of dimensions and associated variables to answer research questions relevant to OABD. [ABSTRACT FROM AUTHOR]

Published
2023
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3. Can magnetic resonance imaging enhance the assessment of potential new treatments for cognitive impairment in mood disorders? A systematic review and position paper by the International Society for Bipolar Disorders Targeting Cognition Task Force

Author

Miskowiak, Kamilla W., primary, Yalin, Nefize, additional, Seeberg, Ida, additional, Burdick, Katherine E., additional, Balanzá‐Martínez, Vicent, additional, Bonnin, Caterina del Mar, additional, Bowie, Christopher R., additional, Carvalho, Andre F., additional, Dols, Annemieke, additional, Douglas, Katie, additional, Gallagher, Peter, additional, Hasler, Gregor, additional, Kessing, Lars V., additional, Lafer, Beny, additional, Lewandowski, Kathryn E., additional, López‐Jaramillo, Carlos, additional, Martinez‐Aran, Anabel, additional, McIntyre, Roger S., additional, Porter, Richard J., additional, Purdon, Scot E., additional, Schaffer, Ayal, additional, Sumiyoshi, Tomiki, additional, Torres, Ivan J., additional, Van Rheenen, Tamsyn E., additional, Yatham, Lakshmi N., additional, Young, Allan H., additional, Vieta, Eduard, additional, and Stokes, Paul R. A., additional

Published
2022
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4. Randomised controlled cognition trials in remitted patients with mood disorders published between 2015 and 2021: A systematic review by the International Society for Bipolar Disorders Targeting Cognition Task Force

Author

Miskowiak, Kamilla W., primary, Seeberg, Ida, additional, Jensen, Mette B., additional, Balanzá‐Martínez, Vicent, additional, del Mar Bonnin, Caterina, additional, Bowie, Christopher R., additional, Carvalho, Andre F., additional, Dols, Annemieke, additional, Douglas, Katie, additional, Gallagher, Peter, additional, Hasler, Gregor, additional, Lafer, Beny, additional, Lewandowski, Kathryn E., additional, López‐Jaramillo, Carlos, additional, Martinez‐Aran, Anabel, additional, McIntyre, Roger S., additional, Porter, Richard J., additional, Purdon, Scot E., additional, Schaffer, Ayal, additional, Stokes, Paul, additional, Sumiyoshi, Tomiki, additional, Torres, Ivan J., additional, Van Rheenen, Tamsyn E., additional, Yatham, Lakshmi N., additional, Young, Allan H., additional, Kessing, Lars V., additional, Burdick, Katherine E., additional, and Vieta, Eduard, additional

Published
2022
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7. Psychological therapies and psychoeducational recommendations for bipolar disorder treatment during COVID‐19 pandemic

Author

Siqueira Rotenberg, Luisa, Nascimento, Camila, Cohab Khafif, Tatiana, Silva Dias, Rodrigo, and Lafer, Beny

Subjects
medicine.medical_specialty, Bipolar Disorder, Pneumonia, Viral, Population, MEDLINE, Psychological Distress, Scientific evidence, Betacoronavirus, 03 medical and health sciences, 0302 clinical medicine, COVID‐19, Pandemic, medicine, Humans, Bipolar disorder, Social isolation, Psychiatry, education, Pandemics, Biological Psychiatry, education.field_of_study, SARS-CoV-2, business.industry, COVID-19, medicine.disease, Mental health, Telemedicine, Patient Care Management, 030227 psychiatry, Psychotherapy, Psychiatry and Mental health, Clinical Care, Social Isolation, Communicable Disease Control, Practice Guidelines as Topic, Critical Pathways, Anxiety, medicine.symptom, Coronavirus Infections, business, and Adjunctive Therapies, 030217 neurology & neurosurgery
Abstract

In the past few months, many lives have been impacted by the new COVID‐19 pandemic, which generateda need for social isolation and quarantine, impacting personal freedom, financial stability, and mental health. During this period, it is expected that many people willexperience higher levels of anxiety and depression.Individualswith pre‐existing anxiety disorders (AD) and other psychiatric conditions are more vulnerable to the negative psychological consequences of pandemics.Individuals with bipolar disorder (BD) are at increased risk of developing AD, with roughlyhalf of this population exhibitingitduring the course of illness1.Recently published guidelines focus mainly on general mental health issues, whereas our clinical care review aims to provide specific guidelines for BD treatment during the COVID‐19 pandemic.All mental health approaches cited in this article are based on scientific evidence.

Published
2020

9. Emotion Regulation and Bipolar Disorder: Strategies during the COVID‐19 Pandemic

Author

Siqueira Rotenberg, Luisa, Cohab Khafif, Tatiana, Nascimento, Camila, and Lafer, Beny

Subjects
Adult, Male, medicine.medical_specialty, Bipolar Disorder, Coronavirus disease 2019 (COVID-19), Physical Distancing, medicine.disease_cause, 03 medical and health sciences, Cognitive Reappraisal, 0302 clinical medicine, Surveys and Questionnaires, Pandemic, Adaptation, Psychological, medicine, Secondary Prevention, Psychological stress, Humans, Bipolar disorder, Clinical care, Psychiatry, Biological Psychiatry, SARS-CoV-2, Social distance, Psychological distress, COVID-19, Bipolar Disorders, medicine.disease, COVID‐ 19 pandemic, 030227 psychiatry, Emotional Regulation, Psychiatry and Mental health, Clinical Care, Social Isolation, Emotion Regulation, Female, Psychology, 030217 neurology & neurosurgery, Stress, Psychological
Abstract

The COVID‐19 pandemic, with necessary measures such as social distancing, has significantly affected people’s habits, and psychological wellbeing. This directly impacts individuals suffering from Bipolar Disorder, since they depend on a well‐balanced routine, regular sleeping hours, and sparse psychological stress, in order to prevent relapses. In this clinical care piece, we discuss Emotion Regulation strategies to help patients deal with the heightened psychological distress inflicted by the current pandemic.

Published
2020

10. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013

Author

Yatham, Lakshmi N, Kennedy, Sidney H, Parikh, Sagar V, Schaffer, Ayal, Beaulieu, Serge, Alda, Martin, OʼDonovan, Claire, MacQueen, Glenda, McIntyre, Roger S, Sharma, Verinder, Ravindran, Arun, Young, Trevor L, Milev, Roumen, Bond, David J, Frey, Benicio N, Goldstein, Benjamin I, Lafer, Beny, Birmaher, Boris, Ha, Kyooseob, Nolen, Willem A, and Berk, Michael

Published
2013
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11. Impact of sunlight on the age of onset of bipolar disorder

Author

Bauer, Michael, Glenn, Tasha, Alda, Martin, Andreassen, Ole A, Ardau, Raffaella, Bellivier, Frank, Berk, Michael, Bjella, Thomas D, Bossini, Letizia, Del Zompo, Maria, Dodd, Seetal, Fagiolini, Andrea, Frye, Mark A, Gonzalez-Pinto, Ana, Henry, Chantal, Kapczinski, Flávio, Kliwicki, Sebastian, König, Barbara, Kunz, Mauricio, Lafer, Beny, Lopez-Jaramillo, Carlos, Manchia, Mirko, Marsh, Wendy, Martinez-Cengotitabengoa, Mónica, Melle, Ingrid, Morken, Gunnar, Munoz, Rodrigo, Nery, Fabiano G, O’Donovan, Claire, Pfennig, Andrea, Quiroz, Danilo, Rasgon, Natalie, Reif, Andreas, Rybakowski, Janusz, Sagduyu, Kemal, Simhandl, Christian, Torrent, Carla, Vieta, Eduard, Zetin, Mark, and Whybrow, Peter C

Published
2012
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14. Affective cognition in bipolar disorder: A systematic review by the ISBD targeting cognition task force

Author

Miskowiak, Kamilla W., primary, Seeberg, Ida, additional, Kjaerstad, Hanne L., additional, Burdick, Katherine E., additional, Martinez‐Aran, Anabel, additional, Bonnin, Caterina, additional, Bowie, Christopher R., additional, Carvalho, Andre F., additional, Gallagher, Peter, additional, Hasler, Gregor, additional, Lafer, Beny, additional, López‐Jaramillo, Carlos, additional, Sumiyoshi, Tomiki, additional, McIntyre, Roger S., additional, Schaffer, Ayal, additional, Porter, Richard J., additional, Purdon, Scot, additional, Torres, Ivan J., additional, Yatham, Lakshmi N., additional, Young, Allan H., additional, Kessing, Lars V., additional, Van Rheenen, Tamsyn E., additional, and Vieta, Eduard, additional

Published
2019
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17. The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONIC‐BD)

Author

Burdick, Katherine E., primary, Millett, Caitlin E., additional, Bonnín, Caterina del Mar, additional, Bowie, Christopher R., additional, Carvalho, Andre F., additional, Eyler, Lisa T., additional, Gallagher, Peter, additional, Harvey, Philip D., additional, Kessing, Lars V., additional, Lafer, Beny, additional, Langenecker, Scott A., additional, Lewandowski, Kathryn E., additional, López‐Jaramillo, Carlos, additional, Marshall, David F., additional, Martinez‐Aran, Anabel, additional, McInnis, Melvin G., additional, McIntyre, Roger S., additional, Miskowiak, Kamilla W., additional, Porter, Richard J., additional, Purdon, Scot E., additional, Ryan, Kelly A., additional, Sumiyoshi, Tomiki, additional, Torres, Ivan J., additional, Van Rheenen, Tamsyn E., additional, Vieta, Eduard, additional, Woodward, Neil D., additional, Yatham, Lakshmi N., additional, and Young, Allan H., additional

Published
2019
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19. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

Author

Yatham, Lakshmi N, primary, Kennedy, Sidney H, additional, Parikh, Sagar V, additional, Schaffer, Ayal, additional, Bond, David J, additional, Frey, Benicio N, additional, Sharma, Verinder, additional, Goldstein, Benjamin I, additional, Rej, Soham, additional, Beaulieu, Serge, additional, Alda, Martin, additional, MacQueen, Glenda, additional, Milev, Roumen V, additional, Ravindran, Arun, additional, O'Donovan, Claire, additional, McIntosh, Diane, additional, Lam, Raymond W, additional, Vazquez, Gustavo, additional, Kapczinski, Flavio, additional, McIntyre, Roger S, additional, Kozicky, Jan, additional, Kanba, Shigenobu, additional, Lafer, Beny, additional, Suppes, Trisha, additional, Calabrese, Joseph R, additional, Vieta, Eduard, additional, Malhi, Gin, additional, Post, Robert M, additional, and Berk, Michael, additional

Published
2018
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20. Physical exercise for bipolar disorder: Time for action.

Author

Lafer, Beny, Neves, Lucas Melo, and Nierenberg, Andrew A.

Subjects
*BIPOLAR disorder, *ATRIAL natriuretic peptides, *BRAIN-derived neurotrophic factor, *BRAIN natriuretic factor, *PEROXISOME proliferator-activated receptors
Abstract

Thus, it is necessary to explore the possible mechanisms involved in the improvements provided by PE intervention in people with BD and if fundamental to apply randomized clinical trials design to verify the potential benefits of PE in BD. Bipolar disorder (BD) is associated with higher rates of sedentarism, metabolic syndrome, obesity, and early onset cardiovascular disease, leading to premature mortality. Furthermore, the relationships among PGC-1 alpha, inflammation, and PE are relevant to BD due to the relationship between BD and high inflammatory markers, metabolic syndrome, and cardiovascular disease. [Extracted from the article]

Published
2022
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21. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013

Author

Yatham, Lakshmi N, primary, Kennedy, Sidney H, additional, Parikh, Sagar V, additional, Schaffer, Ayal, additional, Beaulieu, Serge, additional, Alda, Martin, additional, O’Donovan, Claire, additional, MacQueen, Glenda, additional, McIntyre, Roger S, additional, Sharma, Verinder, additional, Ravindran, Arun, additional, Young, L Trevor, additional, Milev, Roumen, additional, Bond, David J, additional, Frey, Benicio N, additional, Goldstein, Benjamin I, additional, Lafer, Beny, additional, Birmaher, Boris, additional, Ha, Kyooseob, additional, Nolen, Willem A, additional, and Berk, Michael, additional

Published
2012
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23. Stable neural underpinnings of emotional cognition subgroups in patients newly diagnosed with bipolar disorder: A prospective fMRI study.

Author

Kjærstad, Hanne Lie, Siqueira Rotenberg, Luisa, Macoveanu, Julian, Coello, Klara, Faurholt‐Jepsen, Maria, Bjertrup, Anne Juul, Knudsen, Gitte M., Fisher, Patrick M., Vinberg, Maj, Kessing, Lars Vedel, Lafer, Beny, and Miskowiak, Kamilla Woznica

Abstract

Objective Methods Results Conclusions This study aimed to investigate the neural underpinnings of emotional cognition subgroups in recently diagnosed patients with bipolar disorder (BD) and change over time over a 15‐month follow‐up period.Patients and healthy controls (HC) underwent emotional and nonemotional cognitive assessments and functional magnetic resonance imaging (fMRI) at the baseline (BD n = 87; HC n = 65) and at 15‐month follow‐up (BD n = 44; HC n = 38). Neural activity during emotion reactivity and regulation in response to aversive pictures was assessed during fMRI. Patients were clustered into subgroups based on their emotional cognition and, with HC, were compared longitudinally on cognition and neural activity during emotion reactivity and regulation.Patients were optimally clustered into two subgroups: Subgroup 1 (n = 40, 46%) was characterized by heightened emotional reactivity in negative social scenarios, which persisted over time, but were otherwise cognitively intact. This subgroup exhibited stable left amygdala hyper‐activity over time during emotion reactivity compared to subgroup 2. Subgroup 2 (n = 47, 54%) was characterized by global emotional cognitive impairments, including stable difficulties with emotion regulation over time. During emotion regulation across both time points, this group exhibited hypo‐activity in the left dorsolateral prefrontal cortex. Additionally, patients in subgroup 2 had poorer nonemotional cognition, had more psychiatric hospital admissions and history of psychotic episodes than those in subgroup 1.Broad impairments in emotional cognition in approximately half of BD patients and associated nonemotional cognitive deficits may originate from insufficient recruitment of prefrontal resources, contributing to poorer clinical outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Emotion Regulation and Bipolar Disorder: Strategies during the COVID-19 Pandemic.

Author

de Siqueira Rotenberg L, Cohab Khafif T, Nascimento C, and Lafer B

Subjects
Adaptation, Psychological, Adult, Female, Humans, Male, SARS-CoV-2, Secondary Prevention, Social Isolation psychology, Surveys and Questionnaires, Bipolar Disorder epidemiology, Bipolar Disorder psychology, COVID-19 epidemiology, COVID-19 prevention & control, COVID-19 psychology, Emotional Regulation, Physical Distancing, Stress, Psychological etiology, Stress, Psychological prevention & control
Published
2020
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25. Psychological therapies and psychoeducational recommendations for bipolar disorder treatment during COVID-19 pandemic.

Author

de Siqueira Rotenberg L, Nascimento C, Cohab Khafif T, Silva Dias R, and Lafer B

Subjects
Betacoronavirus, COVID-19, Communicable Disease Control methods, Humans, Patient Care Management methods, Patient Care Management trends, Practice Guidelines as Topic, Psychological Distress, SARS-CoV-2, Bipolar Disorder psychology, Bipolar Disorder therapy, Coronavirus Infections epidemiology, Coronavirus Infections prevention & control, Coronavirus Infections psychology, Critical Pathways, Pandemics prevention & control, Pneumonia, Viral epidemiology, Pneumonia, Viral prevention & control, Pneumonia, Viral psychology, Psychotherapy education, Psychotherapy methods, Social Isolation psychology, Telemedicine methods
Published
2020
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