Search

Your search keyword '"Tae-Il Jeon"' showing total 2 results
Start Over Author "Tae-Il Jeon" Journal biotechnology letters
2 results on '"Tae-Il Jeon"'

1. Phellinus linteus grown on germinated brown rice suppresses IgE production by the modulation of Th1/Th2 balance in murine mesenteric lymph node lymphocytes

Author

Tae Il Jeon, Beong Ou Lim, Seong-Gu Hwang, Jae Hak Moon, and Dong Ki Park

Subjects
CD4-Positive T-Lymphocytes, Male, T-Lymphocytes, Lymphocyte, medicine.medical_treatment, Down-Regulation, Bioengineering, Immunoglobulin E, Applied Microbiology and Biotechnology, Interferon-gamma, Mice, Th2 Cells, medicine, Animals, Humans, Lymphocytes, Lymph node, Cells, Cultured, Mice, Inbred ICR, Oryza sativa, biology, Basidiomycota, Oryza, General Medicine, Th1 Cells, biology.organism_classification, Molecular biology, Interleukin-10, medicine.anatomical_structure, Cytokine, Phellinus linteus, Immunology, biology.protein, Brown rice, Interleukin-4, Lymph Nodes, Antibody, Biotechnology
Abstract

We compared the immunomodulating effects of Phellinus linteus (PL), germinated brown rice (BR) and P. linteus grown on germinated brown rice (PB) on IgE production in murine mesenteric lymph node (MLN) lymphocytes. All extracts decreased IgE concentrations by 43--65% compared to control mice in both serum and MLN lymphocytes. In addition, PL and PB increased the proportion of CD4(+) T cells by 9% and 12% in MLN lymphocytes. IFN-gamma concentration, Th1 cytokine, was significantly increased by 44--67%, whereas IL-4 and IL-10 concentrations, Th2 cytokine, significantly decreased by 30--60% in the three treated groups compared to control group. These results suggest that PB suppresses IgE production through the modulation of Th1/Th2 balance to down-regulate Th2 response in MLN lymphocytes, even though a synergistic effect of PB was not found.

Published
2005

2. Extracts of Phellinus linteus grown on germinated brown rice suppress liver damage induced by carbon tetrachloride in rats

Author

Seong-Gu Hwang, Tae Il Jeon, Beong Ou Lim, and Dong Ki Park

Subjects
Cell Extracts, Male, Bioengineering, digestive system, Applied Microbiology and Biotechnology, Antioxidants, Rats, Sprague-Dawley, Superoxide dismutase, Lipid peroxidation, chemistry.chemical_compound, parasitic diseases, medicine, Animals, Food science, Carbon Tetrachloride, Medicine, East Asian Traditional, Liver injury, biology, Chemistry, Basidiomycota, Liver Diseases, Probiotics, Fatty Acids, Cytochrome P-450 CYP2E1, Oryza, General Medicine, CYP2E1, medicine.disease, biology.organism_classification, digestive system diseases, Rats, Treatment Outcome, Biochemistry, Phellinus linteus, Catalase, biology.protein, Carbon tetrachloride, Brown rice, Lipid Peroxidation, Chemical and Drug Induced Liver Injury, Injections, Intraperitoneal, Biotechnology
Abstract

Extracts of Phellinus linteus (EPB), grown on germinated brown rice, protected rats from liver injury induced by carbon tetrachloride (CCl4). Peroxidation products in the liver were decreased to 10% by EPB. Catalase and superoxide dismutase activities were significantly decreased to 55% and 39% by CCl4 administration, but EPB blocked this effect, resulting in enzyme activities at control levels. Expression of cytochrome P450 2E1 (CYP2E1) protein was significantly decreased to 88% in CCl4-treated rats but remained at control levels when EPB was also administered. EPB did not affect the altered fatty acid composition induced by CCl4. The hepatoprotective effect of EPB may be mediated by EPB's prevention of CCl4-induced CYP2E1 degradation.

Published
2003

Catalog

Books, media, physical & digital resources
See catalog results