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The article presents an overview of the history and current status of nuclear transfer cloning. It states that in the early 1900s, some of the earliest research that created clones was carried out by Hans Spemann, a great developmental biologist. Spemann found that he was able to produce twins by dissecting newt embryos up to the early gastrula stage. One of the potential advantages of cloning research is that it is expected to produce high-genetic-value agricultural animals for developing countries.