1. Tailoring chemically converted graphenes using a water-soluble pyrene derivative with a zwitterionic arm for sensitive electrochemiluminescence-based analyses
- Author
-
Je Seung Lee, Joohoon Kim, Jihye Kwon, Yongwoon Lee, and Seo Kyoung Park
- Subjects
Models, Molecular ,Dendrimers ,Biomedical Engineering ,Biophysics ,Nanoparticle ,02 engineering and technology ,Biosensing Techniques ,Conjugated system ,010402 general chemistry ,01 natural sciences ,Luminol ,chemistry.chemical_compound ,Dendrimer ,Electrochemistry ,Electrochemiluminescence ,Organic chemistry ,Aqueous solution ,Luminescent Agents ,Pyrenes ,Tin Compounds ,Water ,General Medicine ,Electrochemical Techniques ,Hydrogen Peroxide ,021001 nanoscience & nanotechnology ,Combinatorial chemistry ,0104 chemical sciences ,Indium tin oxide ,Cholesterol ,chemistry ,Solubility ,Luminescent Measurements ,Pyrene ,Nanoparticles ,Graphite ,0210 nano-technology ,Biotechnology - Abstract
We report a method to tailor chemically converted graphenes (CCGs) using a water-soluble pyrene derivative (1) with a zwitterionic arm, and the feasibility of the tailored CCGs to sensitive electrochemiluminescence (ECL)-based analyses. The compound 1 serves the dual purpose of improving the dispersion of the CCGs in aqueous solutions and further tailoring the catalytic activity of the CCGs with dendrimer-encapsulated catalytic nanoparticles. As a model system, we conjugated dendrimer-encapsulated Pt nanoparticles to the 1-functionalized CCGs on indium tin oxide (ITO) electrodes. The resulting ITOs exhibited significantly increased ECL emission of the luminol/H2O2 ECL system; i.e. two orders-of-magnitude enhancement in the ECL compared to that obtained from bare ITOs, which allowed a ca. 154 times more sensitive ECL-based analysis of cholesterol using the modified ITOs compared with the use of bare ITOs.
- Published
- 2016