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Your search keyword '"Nakamura, Yukio"' showing total 2 results
Start Over Author "Nakamura, Yukio" Topic ph dependence Journal bioscience, biotechnology & biochemistry
2 results on '"Nakamura, Yukio"'

1. The Coexistence of Ser84 in Renin and His13 in Angiotensinogen Brings a pH Profile of Two Separate Peaks to the Reaction of Human Renin and Sheep Angiotensinogen.

Author

Iwata, Hideyuki, Nakagawa, Tsutomu, Yoshioka, Yuichiro, Kagei, Kazufumi, Imada, Kenta, Nakane, Chiaki, Fujita, Hiromi, Suzuki, Fumiaki, and Nakamura, Yukio

Subjects
*RENIN, *ANGIOTENSINS, *SHEEP, *HYDROGEN ions, *HYDROGEN bonding
Abstract

The article reports on the results of a study of the coexistence of Ser84 in renin and His13 in angiotensinogen which brings a pH profile of two separate peaks to the reaction of human renin and sheep angiotensionogen. A description of the experimental set-up and measurement methods is presented. The study indicated that sheep angiotensinogen has a factor other than His13 to enhance the activity of human renin at basic pH.

Published
2008
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2. Ser84 of Human Renin Contributes to the Biphasic pH Dependence of the Renin-Angiotensinogen Reaction.

Author

Iwata, Hideyuki, Nakagawa, Tsutomu, Nishiuchi, Kazuhiro, Hiratsuka, Tomoaki, Satou, Ryousuke, Yoshioka, Yuichiro, Fukui, Youko, Suzuki, Fumiaki, and Nakamura, Yukio

Subjects
*RENIN, *ANGIOTENSINS, *HYDROGEN-ion concentration, *BIOCHEMISTRY, *ASPARTIC proteinases
Abstract

The article investigates the pH dependence of the reaction of various renins using sheep angiotensinogen as a substrate. The pH profile of the human renin reaction showed two separate peaks against sheep angiotensinogen. The article indicates that Ser84 of human renin contributes to the biphasic pH dependence of the renin-angiotensinogen reaction.

Published
2007
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