1. Alkyl derivatives of 1,3,5-triazine as histamine H
- Author
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Dorota, Łażewska, Szczepan, Mogilski, Stefanie, Hagenow, Kamil, Kuder, Monika, Głuch-Lutwin, Agata, Siwek, Małgorzata, Więcek, Maria, Kaleta, Ulla, Seibel, Armin, Buschauer, Barbara, Filipek, Holger, Stark, and Katarzyna, Kieć-Kononowicz
- Subjects
Inflammation ,Analgesics ,Dose-Response Relationship, Drug ,Molecular Structure ,Triazines ,Carrageenan ,Ligands ,Rats ,Mice ,Structure-Activity Relationship ,Formaldehyde ,Animals ,Humans ,Receptors, Histamine H4 - Abstract
This study focuses on the design, synthesis, molecular modeling and biological evaluation of a novel group of alkyl-1,3,5-triazinyl-methylpiperazines. New compounds were synthesized and their affinities for human histamine H
- Published
- 2018