1. Novel skeleton compound Allomyrinanoid A and two purine alkaloids from the adult of Allomyrina dichotoma L
- Author
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Weiping Yin, Gao Jiayu, Junna Liu, Niu Lanlan, and Li Haidi
- Subjects
Purine ,Stereochemistry ,Clinical Biochemistry ,Pharmaceutical Science ,010402 general chemistry ,01 natural sciences ,Biochemistry ,chemistry.chemical_compound ,Alkaloids ,Column chromatography ,Drug Discovery ,Animals ,Organic chemistry ,Norbornane ,Molecular Biology ,Bacteria ,010405 organic chemistry ,Chemistry ,Alkaloid ,Organic Chemistry ,Bacterial Infections ,Oxime ,Norbornanes ,Tautomer ,Anti-Bacterial Agents ,0104 chemical sciences ,Coleoptera ,Solvent ,Purines ,Molecular Medicine ,Two-dimensional nuclear magnetic resonance spectroscopy - Abstract
Three new compounds were isolated from the adult insect of Allomyrina dichotoma L. for the first time. A new skeleton compound is named as Allomyrinanoid A ( 1 ) originated from the familiar norbornane derivatives and two new compounds of purine alkaloid are named as adenine-9-methylaldehyde oxime B ( 2 ) and 6- N -methyleneimine-adenine-9-methylaldehyde oxime B ( 3 ). The compounds ( 2 ) and ( 3 ) are the tautomers of imine–enamine and creatively separated form the solvent using column chromatography method. The structures of all isolated compounds were established by spectroscopic methods including analyses of their 1D, 2D NMR and HRESI-MS data, and confirmed by comparison of the literature data. These new components displayed antibacterial activities against both Gram-positive and Gram-negative strain.
- Published
- 2016