Author: "Kim, Su Yeon" / Journal: bioorganic & medicinal chemistry letters / Topic: resiniferatoxin - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Kim, Su Yeon" Topic resiniferatoxin Journal bioorganic & medicinal chemistry letters

Author: Lee, Jeewoo, Jin, Mi-Kyoung, Kang, Sang-Uk, Kim, Su Yeon, Lee, Jiyoun, Shin, Myoungyoup, Hwang, Jaemin, Cho, Sookhyun, Choi, Yeon-Sil, Choi, Hyun-Kyung, Kim, Sung-Eun, Suh, Young-Ger, Lee, Yong-Sil, Kim, Young-Ho, Ha, Hee-Jin, Toth, Attila, Pearce, Larry V., Tran, Richard, Szabo, Tamas, and Welter, Jacqueline D.
Subjects: *THIOUREA, *UREA, *METABOLISM, *URINALYSIS
Abstract: Abstract: The structure–activity relationships for the ‘B-region’ of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. A docking model of potent antagonist 2 with the sensor region of TRPV1 is proposed. [Copyright &y& Elsevier]
Published: 2005
Full Text: View/download PDF

Author: Lee, Jeewoo, Kang, Sang-Uk, Kil, Min-Jung, Shin, Myoungyoup, Lim, Ju-Ok, Choi, Hyun-Kyung, Jin, Mi-Kyoung, Kim, Su Yeon, Kim, Sung-Eun, Lee, Yong-Sil, Min, Kyung-Hoon, Kim, Young-Ho, Ha, Hee-Jin, Tran, Richard, Welter, Jacqueline D., Wang, Yun, Szabo, Tamas, Pearce, Larry V., Lundberg, Daniel J., and Toth, Attila
Subjects: *THIOUREA, *ORGANOSULFUR compounds, *DRUG antagonism, *HALOGENS
Abstract: Abstract: The structure–activity relationships for the ‘A-region’ of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues have been investigated as TRPV1 receptor antagonists. The 2-halogen analogues showed enhanced antagonism compared to the prototype antagonist. [Copyright &y& Elsevier]
Published: 2005
Full Text: View/download PDF

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