1. The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis
- Author
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Giulio Gasparini, Camillo Azzuni, Roberto Boniello, Umberto Garagiola, Daniela Gasparini, Gianmarco Saponaro, Mattia Todaro, Enrico Foresta, Piero Doneddu, Alessia Adduci, Francesco Di Nardo, S. Pelo, Giuseppe D'Amato, Paolo De Angelis, and Alessandro Moro
- Subjects
Adult ,Male ,Genetics and Molecular Biology (all) ,Drug ,Lidocaine ,Article Subject ,Immunology and Microbiology (all) ,Settore MED/29 - CHIRURGIA MAXILLOFACCIALE ,media_common.quotation_subject ,lcsh:Medicine ,Biochemistry ,General Biochemistry, Genetics and Molecular Biology ,Settore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE ,03 medical and health sciences ,0302 clinical medicine ,Diclofenac ,medicine ,Humans ,Ropivacaine ,030212 general & internal medicine ,Anesthetics, Local ,Stomatitis ,media_common ,General Immunology and Microbiology ,business.industry ,lcsh:R ,030206 dentistry ,General Medicine ,medicine.disease ,Amides ,Topical medication ,Clinical trial ,Oral Aphthosis ,Anesthesia ,Clinical Study ,Female ,Stomatitis, Aphthous ,Multivitamin ,business ,Biochemistry, Genetics and Molecular Biology (all) ,medicine.drug - Abstract
The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients’ part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives.
- Published
- 2018
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