1. Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases
- Author
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França, Paulo H. B., Barbosa, Daniel P., da Silva, Daniel L., Ribeiro, Êurica A. N., Santana, Antônio E. G., Santos, Bárbara V. O., Barbosa-Filho, José M., Quintans, Jullyana S. S., Barreto, Rosana S. S., Quintans-Júnior, Lucindo J., and Araújo-Júnior, João X. de
- Subjects
Article Subject - Abstract
Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases.
- Published
- 2014
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