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Your search keyword '"Leila Najd Hassan Bonab"' showing total 1 results
Start Over Author "Leila Najd Hassan Bonab" Journal biology of sex differences
1 results on '"Leila Najd Hassan Bonab"'

1. Sex, age, and ethnic dependency of lipoprotein variants as the risk factors of ischemic heart disease: a detailed study on the different age-classes and genders in Tehran Cardiometabolic Genetic Study (TCGS)

Author

Hossein Lanjanian, Leila Najd Hassan Bonab, Mahdi Akbarzadeh, Maryam Moazzam-Jazi, Asiyeh Sadat Zahedi, Sajedeh Masjoudi, and Maryam S. Daneshpour

Subjects
TCGS, Lipoprotein (a), Lp(a), LPA locus, Single nucleotide polymorphism, Myocardial infarction (MI), Medicine, Physiology, QP1-981
Abstract

Abstract Biological processes involving environmental and genetic factors drive the interplay between age- and sex-regulating lipid profile. The relation between variations in the LPA gene with increasing the risk of coronary heart disease is dependent on population differences, sex, and age. The present study tried to do a gene candidate association analysis in people with myocardial infarction (MI) in a 22 year cohort family-based longitudinal cohort study, Tehran Cardiometabolic Genetic Study (TCGS). After adjusting p value by the FDR method, only the association of rs6415084 with the MI probability and the age-of-CHD-onset was significant in males in their middle age (p

Published
2022
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