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Start Over Author "Galina N. Filippova" Journal biology of sex differences
1 results on '"Galina N. Filippova"'

1. Sex-biased and parental allele-specific gene regulation by KDM6A

Author

Wenxiu Ma, He Fang, Nicolas Pease, Galina N. Filippova, Christine M. Disteche, and Joel B. Berletch

Subjects
Sex biases, Parent-of-origin, Allele-specific, Imprinting, Gene regulation, Development, Medicine, Physiology, QP1-981
Abstract

Highlights The majority of KDM6A targets are regulated from one allele or the other with allelic downregulation showing a maternal allele bias. Kdm6a knockout affects genes that have been implicated in phenotypes of Kabuki syndrome caused by KDM6A mutations in human. KDM6A facilitates sex-biased gene expression, particularly female-biased expression.

Published
2022
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