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4 results on '"Vittorio Miele"'

1. Risk Assessment and Cholangiocarcinoma: Diagnostic Management and Artificial Intelligence

Author

Vincenza Granata, Roberta Fusco, Federica De Muzio, Carmen Cutolo, Francesca Grassi, Maria Chiara Brunese, Igino Simonetti, Orlando Catalano, Michela Gabelloni, Silvia Pradella, Ginevra Danti, Federica Flammia, Alessandra Borgheresi, Andrea Agostini, Federico Bruno, Pierpaolo Palumbo, Alessandro Ottaiano, Francesco Izzo, Andrea Giovagnoni, Antonio Barile, Nicoletta Gandolfo, and Vittorio Miele

Subjects
cholangiocarcinoma, surveillance, risk assessment, artificial intelligence, radiomics, Biology (General), QH301-705.5
Abstract

Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary liver tumor, with a median survival of only 13 months. Surgical resection remains the only curative therapy; however, at first detection, only one-third of patients are at an early enough stage for this approach to be effective, thus rendering early diagnosis as an efficient approach to improving survival. Therefore, the identification of higher-risk patients, whose risk is correlated with genetic and pre-cancerous conditions, and the employment of non-invasive-screening modalities would be appropriate. For several at-risk patients, such as those suffering from primary sclerosing cholangitis or fibropolycystic liver disease, the use of periodic (6–12 months) imaging of the liver by ultrasound (US), magnetic Resonance Imaging (MRI)/cholangiopancreatography (MRCP), or computed tomography (CT) in association with serum CA19-9 measurement has been proposed. For liver cirrhosis patients, it has been proposed that at-risk iCCA patients are monitored in a similar fashion to at-risk HCC patients. The possibility of using Artificial Intelligence models to evaluate higher-risk patients could favor the diagnosis of these entities, although more data are needed to support the practical utility of these applications in the field of screening. For these reasons, it would be appropriate to develop screening programs in the research protocols setting. In fact, the success of these programs reauires patient compliance and multidisciplinary cooperation.

Published
2023
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2. Lymphadenopathy after BNT162b2 Covid-19 Vaccine: Preliminary Ultrasound Findings

Author

Vincenza Granata, Roberta Fusco, Sergio Venanzio Setola, Roberta Galdiero, Carmine Picone, Francesco Izzo, Roberta D’Aniello, Vittorio Miele, Roberta Grassi, Roberto Grassi, and Antonella Petrillo

Subjects
COVID-19 infection, vaccine, ultrasound, lymphadenopathy, Biology (General), QH301-705.5
Abstract

During a spontaneous and autonomous study, we assessed the ultrasound finding of lymphadenopathy after BNT162b2 Pfizer vaccine. We enrolled 18 patients with 58 lymphadenopathies: in 10 patients, they were in the laterocervical side, while in 8 patients in the axillar site. The largest diameter was 16 mm with a range from 7 to 16 mm (median value = 10 mm). In the same patient, we found different ultrasound nodal findings. A total of 25 nodes showed eccentric cortical thickening with wide echogenic hilum and oval shape. In total, 19 nodes showed asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape. Overall, 10 nodes showed concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape. A total of four nodes showed huge reduction and displacement of the echogenic hilum and round or oval shape. No anomaly was found at the Doppler echocolor study. In conclusion, eccentric cortical thickening with wide echogenic hilum and oval shape, asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape, concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape, and a huge reduction and displacement of the echogenic hilum and round shape are the features that we found in post BNT162b2 Covid-19 Vaccine lymphadenopathies.

Published
2021
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3. Lymphadenopathy after

Author

Vincenza, Granata, Roberta, Fusco, Sergio Venanzio, Setola, Roberta, Galdiero, Carmine, Picone, Francesco, Izzo, Roberta, D'Aniello, Vittorio, Miele, Roberta, Grassi, Roberto, Grassi, and Antonella, Petrillo

Subjects
ultrasound, vaccine, lymphadenopathy, Article, COVID-19 infection
Abstract

Simple Summary Eccentric cortical thickening with wide echogenic hilum and oval shape, asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape, concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape, and huge reduction and displacement of the echogenic hilum and round shape are the features that we found in post BNT162b2 Covid-19 Vaccine lymphadenopathies. Abstract During a spontaneous and autonomous study, we assessed the ultrasound finding of lymphadenopathy after BNT162b2 Pfizer vaccine. We enrolled 18 patients with 58 lymphadenopathies: in 10 patients, they were in the laterocervical side, while in 8 patients in the axillar site. The largest diameter was 16 mm with a range from 7 to 16 mm (median value = 10 mm). In the same patient, we found different ultrasound nodal findings. A total of 25 nodes showed eccentric cortical thickening with wide echogenic hilum and oval shape. In total, 19 nodes showed asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape. Overall, 10 nodes showed concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape. A total of four nodes showed huge reduction and displacement of the echogenic hilum and round or oval shape. No anomaly was found at the Doppler echocolor study. In conclusion, eccentric cortical thickening with wide echogenic hilum and oval shape, asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape, concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape, and a huge reduction and displacement of the echogenic hilum and round shape are the features that we found in post BNT162b2 Covid-19 Vaccine lymphadenopathies.

Published
2021

4. Lymphadenopathy after BNT162b2 Covid-19 Vaccine: Preliminary Ultrasound Findings

Author

Roberta Fusco, Roberta Grassi, Carmine Picone, Roberta Galdiero, Vincenza Granata, Roberto Grassi, Sergio Venanzio Setola, Roberta D’Aniello, Vittorio Miele, Antonella Petrillo, Francesco Izzo, Granata, V., Fusco, R., Setola, S. V., Galdiero, R., Picone, C., Izzo, F., D'Aniello, R., Miele, V., Grassi, R., and Petrillo, A.

Subjects
2019-20 coronavirus outbreak, General Immunology and Microbiology, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Ultrasound, Lymphadenopathy, Echogenicity, Hilum (biology), Anatomy, Biology, General Biochemistry, Genetics and Molecular Biology, COVID-19 infection, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, lcsh:Biology (General), 030220 oncology & carcinogenesis, Ultrasound finding, General Agricultural and Biological Sciences, business, lcsh:QH301-705.5, Vaccine, Cortical thickening
Abstract

During a spontaneous and autonomous study, we assessed the ultrasound finding of lymphadenopathy after BNT162b2 Pfizer vaccine. We enrolled 18 patients with 58 lymphadenopathies: in 10 patients, they were in the laterocervical side, while in 8 patients in the axillar site. The largest diameter was 16 mm with a range from 7 to 16 mm (median value = 10 mm). In the same patient, we found different ultrasound nodal findings. A total of 25 nodes showed eccentric cortical thickening with wide echogenic hilum and oval shape. In total, 19 nodes showed asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape. Overall, 10 nodes showed concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape. A total of four nodes showed huge reduction and displacement of the echogenic hilum and round or oval shape. No anomaly was found at the Doppler echocolor study. In conclusion, eccentric cortical thickening with wide echogenic hilum and oval shape, asymmetric eccentric cortical thickening with wide echogenic hilum and oval shape, concentric cortical thickening with reduction in the width of the echogenic hilum and oval shape, and a huge reduction and displacement of the echogenic hilum and round shape are the features that we found in post BNT162b2 Covid-19 Vaccine lymphadenopathies.

Published
2021

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