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The frequency of cardiovascular diseases (CVD) is increasing day by day worldwide. The CVD may take shape of an epidemic in near future. The contemporary methods for blood pressure (BP) management seem to be inadequate. Lack of information on the underlying mechanism of BP variability could be the prime reason for the failure in curbing this important health issue. Therefore, there is an urgent need for more advanced research on BP and its management. The temporal aspect of BP is emerging as a critical factor in dedicated clinics for hypertension management. The scientists in the West have recognized this aptly and have involved in translating the chronobiological principles in the process of optimization of therapy. The temporal dimensions of BP and its management are least explored in Indian clinics. The entire domain is a grey area in research, and therefore, deserves attention. [ABSTRACT FROM AUTHOR]