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Your search keyword '"Grasselli, Giorgio"' showing total 2 results
Start Over Author "Grasselli, Giorgio" Journal biological psychiatry global open science
2 results on '"Grasselli, Giorgio"'

2. Sensory over-responsivity and aberrant plasticity in cerebellar cortex in a mouse model of syndromic autism

Author

Simmons, Dana H., Busch, Silas E., Titley, Heather K., Grasselli, Giorgio, Shih, Justine, Du, Xiaofei, Wei, Cenfu, Gomez, Christopher M., Piochon, Claire, and Hansel, Christian

Abstract

Autism spectrum disorder (ASD) patients often show altered responses to sensory stimuli as well as motor deficits, including an impairment of delay eyeblink conditioning (EBC), which involves integration of sensory signals in the cerebellum. Here, we identify abnormalities in parallel fiber (PF) and climbing fiber (CF) signaling in mouse cerebellar cortex that may contribute to these pathologies.

Published
2021
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