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Start Over Author "Bernardeschi L" Journal biological psychiatry
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2. Ambulatory polysomnography of never-depressed borderline subjects: A high-risk approach to rapid eye movement latency

Author

Salvatore Smirne, Luigi Ferini-Strambi, Luana Bernardeschi, Marco Battaglia, Laura Bellodi, Battaglia, MARCO MARIA, FERINI STRAMBI, Luigi, Smirne, S, Bernardeschi, L, and Bellodi, Laura

Subjects
Adult, Male, medicine.medical_specialty, Eye Movements, Personality Inventory, Polysomnography, media_common.quotation_subject, Population, Rapid eye movement sleep, Sleep, REM, Audiology, Borderline Personality Disorder, Surveys and Questionnaires, medicine, Humans, education, Psychiatry, Borderline personality disorder, Biological Psychiatry, media_common, Psychiatric Status Rating Scales, Depressive Disorder, education.field_of_study, medicine.diagnostic_test, Eye movement, Electroencephalography, medicine.disease, Mood disorders, Ambulatory, Female, Psychology, Vigilance (psychology)
Abstract

The sleep parameters of never-depressed borderline subjects and age- and sex-matched normal controls were compared by continuous 48-hr ambulatory electroencephalographic (EEG) monitoring. Borderline subjects had a significantly shorter rapid eye movement latency, normal architecture of rapid eye movements sleep, and had familial risks for mood disorders four times greater than in the families of controls. Reduced latency of rapid eye movement can be a trait indicator of liability to depression, present before the clinical appearance of the disorder, and demonstrable in a putative high-risk population.

Published
1993
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