1. TRAIT (TRAnscript Integrated Table): a knowledgebase of human skeletal muscle transcripts.
- Author
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Toppo S, Cannata N, Fontana P, Romualdi C, Laveder P, Bertocco E, Lanfranchi G, and Valle G
- Subjects
- Documentation, Expressed Sequence Tags, Humans, Information Storage and Retrieval methods, Sequence Analysis, DNA methods, Software, User-Computer Interface, Database Management Systems, Databases, Genetic, Muscle Proteins genetics, Muscle Proteins metabolism, Muscle, Skeletal metabolism, Sequence Alignment methods, Transcription, Genetic genetics
- Abstract
TRAIT is a knowledgebase integrating information on transcripts with related data from genome, proteins, ortholog genes and diseases. It was initially built as a system to manage an EST-based gene discovery project on human skeletal muscle, which yielded over 4500 independent sequence clusters. Transcripts are annotated using automatic as well as manual procedures, linking known transcripts to public databases and unknown transcripts to tables of predicted features. Data are stored in a MySQL database. Complex queries are automatically built by means of a user-friendly web interface that allows the concurrent selection of many fields such as ontology, expression level, map position and protein domains. The results are parsed by the system and returned in a ranked order, in respect to the number of satisfied criteria.
- Published
- 2003
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