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Your search keyword '"Ranganathan, Shoba"' showing total 9 results
Start Over Author "Ranganathan, Shoba" Journal bioinformatics
9 results on '"Ranganathan, Shoba"'

9. iSwathX: an interactive web-based application for extension of DIA peptide reference libraries.

Author

Noor, Zainab, Mohamedali, Abidali, Ranganathan, Shoba, Wu, Jemma X, Pascovici, Dana, Molloy, Mark P, and Baker, Mark S

Subjects
DATA mining, PEPTIDES, MASS spectrometry, PROTEIN-protein interactions, BIOINFORMATICS
Abstract

Summary Large-scale peptide mass spectrometry (MS)/MS reference libraries are essential for the comprehensive analysis of data-independent acquisition (DIA) MS datasets, providing a comprehensive set of spectra for identification and quantification of proteins. We have developed a novel web-based R-package (iSwathX) for combining reference libraries that is compatible with different DIA analysis software. This open-source web GUI automates the process of normalization and combination of spectral libraries and provides a user-friendly method for performing library format conversions, analysis and visualizations, with no need for programing familiarity. Availability and implementation iSwathX is freely accessible at https://biolinfo.shinyapps.io/iSwathX with the R-package and Shiny source code available from GitHub (https://github.com/znoor/iSwathX). Supplementary information Supplementary data are available at Bioinformatics online. [ABSTRACT FROM AUTHOR]

Published
2019
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