1. Bioengineered
- Author
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Xiomara, Fernández-Garibay, María A, Ortega, Estefanía, Cerro-Herreros, Jordi, Comelles, Elena, Martínez, Rubén, Artero, Juan M, Fernández-Costa, and Javier, Ramón-Azcón
- Subjects
Myoblasts ,Muscle Fibers, Skeletal ,Animals ,Humans ,Myotonic Dystrophy ,Cell Differentiation ,Muscle, Skeletal - Abstract
Myotonic dystrophy type 1 (DM1) is the most common hereditary myopathy in the adult population. The disease is characterized by progressive skeletal muscle degeneration that produces severe disability. At present, there is still no effective treatment for DM1 patients, but the breakthroughs in understanding the molecular pathogenic mechanisms in DM1 have allowed the testing of new therapeutic strategies. Animal models and
- Published
- 2020