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Start Over Author "Sidorin, S. S." Journal biochemistry biokhimiia
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1. Metabolic dysfunction and relationship in human frontoparietal cortex in severe traumatic brain injury: single-voxel (1)H magnetic resonance spectroscopy study.

Author

Semenova NA, Akhadov TA, Petryaykin AV, Sidorin SS, Lukovenkov AV, and Varfolomeev SD

Subjects
Adolescent, Aspartic Acid analogs & derivatives, Aspartic Acid metabolism, Brain, Brain Injuries diagnostic imaging, Child, Child, Preschool, Choline metabolism, Creatine metabolism, Female, Humans, Inositol metabolism, Magnetic Resonance Imaging, Male, Radiography, Brain Injuries metabolism, Cerebral Cortex diagnostic imaging, Cerebral Cortex metabolism
Abstract

(1)H-magnetic resonance spectroscopy revealed that apparently normal (from the data of magnetic resonance imaging) human brain frontoparietal cortex in the subacute stage of traumatic brain injury is characterized by decreased level of N-acetylaspartate (NAA) and increase in levels of myoinositol, choline-containing compounds (Cho), and creatine/phosphocreatine (Cr). Correlations between Cr, Cho, and NAA were established. We propose a scheme of neuronal metabolic processes that joins these substances.

Published
2012
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