Search

Your search keyword '"Zheng, Ya-Jun"' showing total 3 results
Start Over Author "Zheng, Ya-Jun" Journal biochemistry
3 results on '"Zheng, Ya-Jun"'

1. Structural definition of the active site and catalytic mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase

Author

Liao, Der-Ing, Zheng, Ya-Jun, Viitanen, Paul V., and Jordan, Douglas B.

Subjects
Biochemistry -- Research, Phosphates -- Physiological aspects, Enzymes -- Physiological aspects, Ligands -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the L-3,4-dihydroxy-2-butanone-4-phosphate synthase from Magnaporthe grisea. The X-ray crystal structures of this synthase has been examined and the high-resolution structures of the enzyme complexed with ligands are presented.

Published
2002

2. Roles of substrate distortion and intramolecular hydrogen bonding in enzymatic catalysis by scytalone dehydratase

Author

Zheng, Ya-Jun, Basarab, Gregory S., and Jordan, Douglas B.

Subjects
Hydrogen bonding -- Analysis, Catalysis -- Analysis, Enzymes -- Structure-activity relationship, Enzyme kinetics -- Analysis, Biological sciences, Chemistry
Abstract

Site-directed mutagenesis of the active-site residues and substrate substitution studies point out to the importance of hydroxyl group for substrate recognition and catalysis by scytalone dehydratase.

Published
2002

3. Stereochemistry of the enolization of scytalone by scytalone dehydratase

Author

Jordan, Douglas B., Zheng, Ya-Jun, Lockett, Bruce A., and Basarab, Gregory S.

Subjects
Enzymes -- Research, Stereochemistry -- Research, Biological sciences, Chemistry
Abstract

The fungal enzyme scytalone dehydratase catalyzes a syn elimination on scytalone by protonating the carbonyl to form an enol. Researches are creating inhibitors of this enzyme to control rice blast.

Published
2000

Catalog

Books, media, physical & digital resources
See catalog results