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Your search keyword '"ZHANG Yu-zhu"' showing total 2 results
Start Over Author "ZHANG Yu-zhu" Journal biochemistry
2 results on '"ZHANG Yu-zhu"'

1. The conformation of NADH bound to inosine 5'-monophosphate dehydrogenase determined by transferred nuclear overhauser effect spectroscopy

Author

Schalk-Hihi, Celine, Zhang, Yu-Zhu, and Markham, George D.

Subjects
Inositol -- Research, Dehydrogenases -- Research, Overhauser effect (Nuclear physics) -- Research, Biological sciences, Chemistry
Abstract

A study was conducted to analyze NADH conformation bound to inosine 5'-monophosphate dehydrogenase using transferred nuclear overhauser effect spectroscopy. An Indigo II Silicon Graphics computer was utilized to analyze nuclear magnetic resonance data while the adenosine and dihydronicottinamide riboside moieties of NADH were analyzed separately. Results showed that the glycosidic conformations of nitoinamide-ribose and adenosine moieties are anti.

Published
1998

2. Structure, stability, and function of hDim1 investigated by NMR, circular dichroism, and mutational analysis

Author

Zhang, Yu-Zhu, Cheng, Hong, Gould, Kathleen L., Golemis, Erica A., and Roder, Heinrich

Subjects
Genetic engineering -- Research, Proteins -- Physiological aspects, Amino acids -- Physiological aspects, Gene mutations -- Physiological aspects, Circular dichroism -- Research, Nuclear magnetic resonance -- Usage, Biochemistry -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on human Dim1 protein which is part of the complex required for pre-mRNA splicing and which interacts with splicing-associated proteins. The authors have investigated the structural basis of its function via the study of the solution structure of the negative human hDim1 protein's reduced form using multidimensional NMR spectroscopy.

Published
2003

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