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Your search keyword '"Holloway, Stephen"' showing total 5 results
Start Over Author "Holloway, Stephen" Journal biochemistry
5 results on '"Holloway, Stephen"'

3. X-ray crystallographic and analytical ultracentrifugation analyses of truncated and full-length yeast copper chaperones for SOD (LYS7): a dimer-dimer model of LYS7-SOD associations and copper delivery

Author

Hall, Leslie T., Sanchez, Raylene J., Holloway, Stephen P., Zhu, Haining, Stine, Jennifer E., Lyons, Thomas J., Demeler, Borries, Schirf, Virgil, Hansen, Jeffrey C., Nersissian, Aram M., Valentine, Joan Selverstone, and Hart, P. John

Subjects
Biochemistry -- Research, X-ray crystallography -- Analysis, Yeast -- Analysis, Copper -- Analysis, Zinc -- Research, Superoxide -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on the copper-zinc superoxide dismutase. The characterization of the truncated and full-length forms of the yeast copper chaperone for SOD has been carried out.

Published
2000

4. Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q

Author

Winkler, Duane D., Schuermann, Jonathan P., Xiaohang Cao, Holloway, Stephen P., Borchelt, David R., Carroll, Mark C., Proescher, Jody B., Culotta, Valeria C., and Hart, P. John

Subjects
Copper -- Chemical properties, Glutamine -- Chemical properties, Histidine -- Chemical properties, Mutation (Biology) -- Analysis, Superoxide dismutase -- Chemical properties, Superoxide dismutase -- Structure, Biological sciences, Chemistry
Abstract

The characteristics, as well as the structural and biophysical properties of His46Arg (H46R) and His48Gln (H48Q), two pathogenic superoxide dismutase (SOD1) mutations are discussed. These variants are shown to exhibit an ablated copper-binding site and are also able to form stable heterocomplexes with copper chaperone for SOD1.

Published
2009

5. X-ray Crystallographic and Analytical Ultracentrifugation Analyses of Truncated and Full-Length Yeast Copper Chaperones for SOD (LYS7): A Dimer−Dimer Model of LYS7−SOD Association and Copper Delivery,

Author

Hall, Leslie T., primary, Sanchez, Raylene J., additional, Holloway, Stephen P., additional, Zhu, Haining, additional, Stine, Jennifer E., additional, Lyons, Thomas J., additional, Demeler, Borries, additional, Schirf, Virgil, additional, Hansen, Jeffrey C., additional, Nersissian, Aram M., additional, Valentine, Joan Selverstone, additional, and Hart, P. John, additional

Published
2000
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