Search

Your search keyword '"Barril, X."' showing total 1 results
Start Over Author "Barril, X." Journal biochemistry
1 results on '"Barril, X."'

1. 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 angstrom resolution: kinetic and molecular dynamic correlates

Author

Dvir, H., Wong, D.M., Harel, M., Barril, X., Orozco, M., Luque, F.J., Munoz-Torrero, D., Camps, P., Rosenberry, T.L., Silman, I., and Sussman, J.L.

Subjects
Acetylcholinesterase -- Research, Enzyme inhibitors -- Analysis, Binding sites (Biochemistry) -- Analysis, Molecular structure -- Analysis, Structure-activity relationships (Biochemistry) -- Analysis, Biological sciences, Chemistry
Abstract

The kinetics of the binding of huprine X inhibitor to the Torpedo californica acetylcholinesterase reveal that it binds to the anionic site and obstructs access to the esteratic site as shown by molecular dynamics simulation of the huprine X inhibitor/enzyme complex crystal structure.

Published
2002

Catalog

Books, media, physical & digital resources
See catalog results