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Your search keyword '"Addition polymerization -- Methods"' showing total 2 results
Start Over Descriptor "Addition polymerization -- Methods" Journal biochemistry
2 results on '"Addition polymerization -- Methods"'

1. Transthyretin aggregation under partially denaturing conditions is a downhill polymerization

Author

Hurshman, Amy R., White, Joleen T., Powers, Evan T., and Kelly, Jeffery W.

Subjects
Hydrogen-ion concentration -- Chemical properties, Amyloidosis -- Analysis, Addition polymerization -- Methods, Polymerization -- Methods, Biological sciences, Chemistry
Abstract

Studies done to demonstrate that M-TTR (monomeric variant of transthyretin) amyloidogenesis at low pH is a complex, multistep reaction whose kinetic behavior is incompatible with the expectations for a nucleation-dependent polymerization is reported. Results of the study suggest that amyloid formation by M-TTR under partially denaturing conditions is a downhill polymerization, in which the highest energy species is the native monomer.

Published
2004

2. Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity

Author

Gupta, Kamlesh and Panda, Dulal

Subjects
Tubulins -- Physiological aspects, Cell proliferation -- Research, Chemical inhibitors -- Physiological aspects, Biochemistry -- Research, Addition polymerization -- Methods, Polymerization, Microtubules -- Physiological aspects, Quercetin -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the dietary flavonoid quercetin. Results demonstrate that quercetin inhibits microtubule polymerization and depolymerizes microtubules made from purified tubulin.

Published
2002

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