1. Photobilirubin II
- Author
-
Bonnett, R, Buckley, D G, Hamzetash, D, Hawkes, G E, Ioannou, S, and Stoll, M S
- Subjects
Chemistry ,Chemical Phenomena ,Isomerism ,Spectrophotometry ,Methanol ,Bilirubin ,Dimethyl Sulfoxide ,Cell Biology ,Molecular Biology ,Biochemistry ,Research Article - Abstract
An improved preparation of photobilirubin II in ammoniacal methanol is described. Evidence is presented which distinguishes between the two structures proposed earlier for photobilirubin II in favour of the cycloheptadienyl structure. Nuclear-Overhauser-enhancement measurements with bilirubin IX alpha and photobilirubin II in dimethyl sulphoxide are complicated by the occurrence of negative and zero effects. The partition coefficient of photobilirubin II between chloroform and phosphate buffer (pH 7.4) is 0.67.
- Published
- 1984
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