Search

Your search keyword '"Davies, Andrew P."' showing total 1 results
Start Over Author "Davies, Andrew P." Journal biochemical & biophysical research communications
1 results on '"Davies, Andrew P."'

1. Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3.

Author

Tu, Yihui, Xue, Huaming, Francis, Wendy, Davies, Andrew P., Pallister, Ian, Kanamarlapudi, Venkateswarlu, and Xia, Zhidao

Subjects
*LACTOFERRIN, *DEXAMETHASONE, *CARTILAGE cells, *CELLULAR signal transduction, *GENETIC regulation, *APOPTOSIS, *DNA damage, *OSTEOARTHRITIS
Abstract

Highlights: [•] Dex exerts dose-dependant inhibition of HACs viability and induction of apoptosis. [•] Dex-induced impairment of chondrocytes was attenuated by rhLF. [•] ERK and FASL/FAS signaling are involved in the effects of rhLF. [•] OA patients with glucocorticoid-induced cartilage damage may benefit from treatment with rhLF. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results