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Cerebellar ataxia is a form of ataxia originating in the cerebellum (the part of brain that is incharge of balance and coordination). Cerebellar ataxia can occur as a result of many diseases and may present with symptoms of inability to coordinate balance, gait, extremity and eye movements. In cerebellar ataxia progressive atrophy of cerebellum occurs. This can be compared to Mastulungshya in Ayurveda. Case Presentation- A 27 years male adult with the complaint of difficulty in walking, writing and difficulty in speaking since two years and also inability in doing daily activities of life got admitted in the Panchkarma male ward. On the basis of clinical features and investigation reports of MRI and CT of the brain, diagnosis done was Spino-Cerebellar ataxia. Management and Outcome- Aacharya Chakrapaani told that Mastishkya as Shirogata sneha (ca.sha 7/15) and atrophy means Kshya of Shirogata sneha. Patient was treated according to above principle, Brihana Chikitsa along Panchkarma procedures like Mustaadi yapna basti and Sarvang abhyang and Shashtikshali pindswedan was done for one month. Significant improvement was seen in clinical features. Patient walking distance increased from 100 meters to 2-3km daily without fatigue. BARS score was reduced from 12 to 6. His speech was improved and easily understandable. Discussion- In the present case, already damaged part was not recovered but the further progressive damage was prevented. Also there was significant improvement in clinical features. Ayurveda says Vyadhiviprit chikitsa sidhaant i.e., Brihana chikitsa in Kshyapradhan vyadhi. The Vyadhinidaan according to Ayurveda sidhant and treating them accordingly may be helpful in many neurological disorders.

Among the various Ras dravyas (mineral drugs), Abhraka Bhasma (incinerated mica ash) is widely used in therapeutics. Many herbal and other organic materials have been quoted in reference for various procedures in preparing Abhraka bhasma. It is wonderful that different pharmacological action has been attributed to different Dravyas used in the pharmaceutical processing of Abhraka Bhasma. However, to establish the safety of such metallic and mineral formulation it is the need of the hour to generate scientific data for such drugs. In the present study two samples of Abhraka Bhasma were prepared using two different methods. The safety profile of Abhraka Bhasma samples (AB-1 & AB-2) were evaluated by conducting acute and subacute toxicity study as per OECD Guidelines. Both acute and sub-acute toxicity study demonstrated safety of AB-1 and AB-2 when administered at therapeutic dose, TED X5 dose and TED X10 dose. Even though the sample AB-1 was prepared using a smaller number of Puta, it was sufficient for preparing good quality of Bhasma and was non-toxic