1. The effect of Phytopaj)Ferula assa-foetida L. oleo gum resin and tragacanth(in patients with COVID-19: A randomized clinical trial.
- Author
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Bahrami-Taghanaki, Hamid Reza, Hoseinzadeh, Hamidreza, Hamedi, Shokouhsadat, Nejad-Bajestani, Majid Jafari, Esmaeilzadeh, Nayereh, Abdollahzadeh, Hasan, Hoseini-asil, Seyedehmasoume, Haghighi, Gholamreza, and Bojdi, Amin
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COVID-19 , *CLINICAL trials , *GUMS & resins , *FERULA , *LYMPHOCYTE count - Abstract
Objective: Exogenous hydrogen sulfide (H2S) has a positive effect on respiratory diseases. Oleo-gum of Ferula assa-foetida contains this compound. This study assessed the effects of Ferula assa-foetida L. oleo gum resin and tragacanth (Phytopaj) on patients with COVID-19. Materials and Methods: A randomized, single-blinded, controlled trial (RCT) phase 2 was conducted in Mashhad on hospitalized COVID-19 patients. In this RCT, 122 patients were randomly assigned to either receive a 14-day oral phytopaj plus ordinary treatment or ordinary treatment only. Changes in peripheral blood lymphocyte count (LC) and blood oxygen saturation (PO2) were the endpoints. Results: Mean±SD of PO2 in Phytopaj comparison ordinary treatment before intervention was 91.86±4.62 and 91.41±9.18, after the intervention it was 93.22±4.26 and 91.91±5.92 mmHg; before intervention, mean±SD of peripheral blood lymphocyte count was 1015.90±500.55, and 1104.28±543.61, and after intervention, it was 1652.27±921.38 and 1326.12±719.28/μL respectively. Conclusion: Phyopaj is most useful in moderate stages of Covid19, and it is not recommended for elderly patients and patients with comorbidity until more insight is gained. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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