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Maffucci syndrome is a rare condition that affects the skin and bones, particularly the limbs. It is characterized by multiple enchondromas (benign bone tumors) and lymphovascular proliferations, such as hemangiomas and venous malformations. Lymphatic malformations, specifically lymphangiomas, have been reported in a few cases. The syndrome is associated with genetic mutations and carries a risk of developing various malignancies. The article presents a case of Maffucci lymphangioma syndrome in a woman with lesions on her lower limb. A skin biopsy confirmed the diagnosis, and genetic testing revealed a mutation associated with Maffucci syndrome. The authors emphasize the importance of recognizing this condition and conducting appropriate follow-up due to the risk of malignant transformation and other malignancies. [Extracted from the article]

Psoriasis is a chronic inflammatory dermatosis affecting 2% of the world's population.[1] Though recognised for its expression on the skin, it is accompanied by chronic systemic inflammation. Relative expression levels of each biomarker are shown in Fig.. Statistical analysis showed significant differences between the biomarkers' relative expressions ( I P i < I i 0.001). None of the biomarkers correlated with BMI; however, relative expression of IL12p40 was higher among patients categorised as overweight or obese ( I P i = I i 0.039). [Extracted from the article]