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2. Transbronchial fluorescence detection of a porphysome-laden tumor in an orthotopic lung cancer mouse model (mouse 1 in Figure 2). The tumor was localized in the cranial lobe. A part of the tumor at the entrance of the cranial lobe bronchus is easily seen by the composite optical fiberscope (COF), with a sharp contrast in fluorescence relative to the adjacent bronchial wall

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