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Start Over Author "M. Niranjan" Journal asian journal of pharmaceutical analysis
4 results on '"M. Niranjan"'

3. Eco-Friendly Spectrophotometric Estimation of Gliclazide using Hydrotropic Solubilization Technique

Author

B Ishwarya, G Jyothi, D Anjiah, G Satheesh Kumar, D Ajay Kumar, D Shravan Kumar, P Bhavani, M. Niranjan Babu, G Sandeep Kumar, and Subhashis Debnath

Subjects
chemistry.chemical_compound, Chromatography, chemistry, Solubilization, Water soluble drug, medicine, Gliclazide, Environmentally friendly, Quantitative determination, Dosage form, medicine.drug, Trisodium citrate
Abstract

In the projected analysis work, a successful; attempt was made to develop simple, accurate, novel, ecofriendly and precise technique for the estimation of poorly water soluble drug Gliclazide in single drug containing dosage form. In the present investigation, a mixed hydrotropic blend of 2M urea and 6M trisodium citrate was used for quantitative determination. Gliclazide showed λ-max at 225 nm and beer's law was obeyed with in the concentration range of 4μg/ml-12μg/ml with mean recovery ranging from 95.33% to 96.35%. The developed technique was validated as per ICH guidelines.

Published
2019

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