Search

An efficient Tf2O‐mediated regioselective C(sp2)−H sulfenylation of enaminones has been described. Methyl sulfoxides are employed as sulfur sources to react with different types of enaminones under mild reaction conditions, providing a straightforward approach for the synthesis of β‐amino sulfides in up to 97% yield via one‐pot manner. Moreover, this sulfenylation proceeded smoothly with oxidant‐free and metal‐free. [ABSTRACT FROM AUTHOR]

An efficient CAN‐mediated C−C bond formation in the oxidative reactions of xanthenes with enaminones under mild reaction conditions are described. A variety of 9H‐xanthene‐9‐ylidene aldehydes could be synthesized in up to 90% yield via one‐pot manner with good functional group compatibility, which achieved the simultaneous construction of carbon‐carbon double bond and carbon‐oxygen double bond. [ABSTRACT FROM AUTHOR]

Abstract: We present a silver‐catalyzed reaction of acceptor‐enynals with alkynes to assemble tetracyclic framework of fluorenols efficiently, in which the reaction was proposed to proceed through an unfavorable 6‐endo‐dig cyclization, followed by a tandem [4+2] cycloaddition/Friedel–Crafts reaction. The reaction could be conducted in one pot for diaryl alkynes substrates. For terminal aryl alkyne or arylalkyl alkyne substrates, the Friedel–Crafts reaction has to be performed in the absence of alkynes. The control reactions demonstrated that there was competition between [Ag]⋅⋅⋅alkyne and [Ag]⋅⋅⋅O=CR2. [ABSTRACT FROM AUTHOR]