Search

An efficient access to a large array of diarylmethane thioether derivatives is developed through catalyst‐free 1,6‐conjugate addition of 1,4‐dithiane‐2,5‐diols with para‐quinone methides in high to excellent yields. Moreover, this reaction system is also suitable for other sulfur‐based nucleophiles, and the resulting products can be readily converted into other valuable diarylmethane derivatives. [ABSTRACT FROM AUTHOR]

A catalyst‐free protocol for synthesizing a new series of indeno[1,2‐b][1,6]naphthyridine‐1,10(2H)‐dione derivatives with good to excellent yields was established based on microwave‐assisted domino reaction of 4‐aminopyridin‐2(1H)‐ones, aldehydes and 1H‐indene‐1,3(2H)‐dione in water. The present approach exhibited useful and green features, such as water as reaction solvent, catalyst‐ and additive‐ free, short reaction time (20–30 min), as well as ease of desired products separation and purification without the need for column chromatography. Also to note, up to four new bonds were formed accompanied by generating water as sole by‐product in this one‐pot procedure. [ABSTRACT FROM AUTHOR]

Herein, a specialized review of the origin and state of the art of proline‐derived long‐aliphatic‐chain amphiphilic organocatalysts (PDLACAOs) and their use in asymmetric organic reactions in aqueous media (water, brine, and sea water), including in water and in the presence of water, is presented. The reactions in which they have been evaluated and the most important mechanisms are discussed. [ABSTRACT FROM AUTHOR]

An efficient rhodium(III)‐catalyzed C−H bond naphthylation reaction is described for the synthesis of diverse anilides and benzamides bearing naphthyl substituents. The substrate scope is broad. The products could be facilely elaborated to various synthetically useful intermediates. To the best of our knowledge, using 7‐azabenzonorbornadienes to achieve naphthylation via transition‐metal‐catalyzed C−H activation has not been reported before. [ABSTRACT FROM AUTHOR]