Search

The article titled "Total Synthesis of Eutyscoparol A and Violaceoid C" in the Asian Journal of Organic Chemistry discusses the successful synthesis of eutyscoparol A and violaceoid C by Takatsugu Murata, Isamu Shiina, and their colleagues. The researchers used a desymmetrization strategy to synthesize these compounds, with the cover picture of the article depicting the symmetric skeleton of quinol intermediates. Eutyscoparol A was also found to be isolated from the endogenous bacterium Eutypella scoparia SCBG-8, which is associated with the Myrtaceae plant. The article provides valuable insights into the total synthesis of these compounds and their natural sources. [Extracted from the article]

Cover Feature: Kinetic Resolution of Racemic 2-Hydroxyarylketones by Asymmetric Esterification: Investigation of the Influence of the Co-Base on the Selectivity (Asian J. Org. A spinning top is a popular play around the world and "Koma" playing is considered an auspicious activity in Japan. The clockwise spinning top and the counterclockwise spinning top correspond to mirror images, and these enantiomers can be created separately via enantioselective synthesis. [Extracted from the article]

An efficient kinetic resolution of a variety of racemic 2‐hydroxyarylketone derivatives was developed by asymmetric esterification protocol using diphenylacetic acid, pivalic anhydride, and a catalytic amount of (R)‐benzotetramisole ((R)‐BTM). It was revealed that employing a tertiary amine as a co‐base in this reaction is not necessary to achieve high s‐values. All conducted reactions proceeded smoothly with good s‐values under the optimized reaction conditions, irrespective of the steric and electronic nature of the substituents on the aromatic rings of the substrates. The most stable transition state of the reaction was determined by density functional theory (DFT) calculations. [ABSTRACT FROM AUTHOR]